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Dementia Care Practice.
Alzheimers Dement
December 2024
Noesis Cognitive Center & Tech Solutions Ltd, Nicosia, Cyprus.
Background A 92-year-old retired seamstress, born in 1932, with 12 years of education, had been residing in a long-term care facility since 2019, following a fall and hip fracture. Post-admission, her cognitive function gradually declined and she did not participate in residential home activities. This study explores the outcomes of an 8-month, multisensory remediation program.
View Article and Find Full Text PDFLongitudinal strain enhancement and bending deformations in piezoceramics.
Nature
January 2025
Department of Materials Engineering, Indian Institute of Science, Bangalore, India.
Piezoelectric materials directly convert between electrical and mechanical energies. They are used as transducers in applications such as nano-positioning and ultrasound imaging. Improving the properties of these devices requires piezoelectric materials capable of delivering a large longitudinal strain on the application of an electric field.
View Article and Find Full Text PDFSystematic searches for new inorganic materials assisted by materials informatics.
Sci Technol Adv Mater
November 2024
Faculty of Materials Science and Engineering, Kyoto Institute of Technology, Kyoto, Japan.
We introduce our proprietary Materials Informatics (MI) technologies and our chemistry-oriented methodology for exploring new inorganic functional materials. Using machine learning on crystal structure databases, we developed 'Element Reactivity Maps' that displays the presence or the predicted formation probability of compounds for combinations of 80 × 80 × 80 elements. By analysing atomic coordinates with Delaunay tetrahedral decomposition, we established the concept of Delaunay Chemistry.
View Article and Find Full Text PDFOptimal Position and Orientation of an Ossicular Accelerometer for Human Auditory Prostheses.
Sensors (Basel)
December 2024
Department of Mechanical Engineering, University of Michigan, 2350 Hayward St., Ann Arbor, MI 48109, USA.
In this study, a method for determining the optimal location and orientation of an implantable piezoelectric accelerometer on the short process of the incus is presented. The accelerometer is intended to be used as a replacement for an external microphone to enable totally implantable auditory prostheses. The optimal orientation of the sensor and the best attachment point are determined based on two criteria-maximum pressure sensitivity sum and minimum loudness level sum.
View Article and Find Full Text PDFInvestigating How Genomic Contexts Impact IS5 Transposition Within the Genome.
Microorganisms
December 2024
Department of Molecular Biology, School of Biological Sciences, University of California at San Diego, 9500 Gilman Dr, La Jolla, CA 92093-0116, USA.
Insertions of the transposable element IS5 into its target sites in response to stressful environmental conditions, DNA structures, and DNA-binding proteins are well studied, but how the genomic contexts near IS5's native loci impact its transpositions is largely unknown. Here, by examining the roles of all 11 copies of IS5 within the genome of strain BW25113 in transposition, we reveal that the most significant copy of IS5 is one nested within and oriented in the same direction as the gene, while two other copies of IS5 harboring point mutations are hardly transposed. Transposition activity is heavily reliant on the upstream promoter that drives IS5 transposase gene , with more transpositions resulting from greater promoter activity.
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