The data on the use of rabies antitoxin obtained by the method ensuring the isolation of active immunoglobulin fractions are presented. The trial was carried out in the Kazakh SSR and the Uzbek SSR. The preparation was injected to subjects bitten by animals, in doses of 5 to 40 ml, depending on the localization of bites, the character of lesions and the age of victims. Antitoxin " Prosdis -4" was found to possess low reactogenicaty . During the term of observation (1 year) no cases of rabies were registered among the immunized victims.
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