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This study aimed to develop a real-time, noninvasive hyperkalemia monitoring system for dialysis patients with chronic kidney disease. Hyperkalemia, common in dialysis patients, can lead to life-threatening arrhythmias or sudden death if untreated. Therefore, real-time monitoring of hyperkalemia in this population is crucial.

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Lead-Grouped Multi-Stage Learning for Myocardial Infarction Localization.

Methods

January 2025

School of Design, Hunan University, Changsha, 410082, China. Electronic address:

The electrocardiogram (ECG) is a ubiquitous medical diagnostic tool employed to localize myocardial infarction (MI) that is characterized by abnormal waveform patterns on the ECG. MI is a serious cardiovascular disease, and accurate, timely diagnosis is crucial for preventing severe outcomes. Current ECG analysis methods mainly rely on intra- and inter-lead feature extraction, but most models overlook the medical knowledge relevant to disease diagnosis.

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Multiscale feature enhanced gating network for atrial fibrillation detection.

Comput Methods Programs Biomed

January 2025

College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, PR China. Electronic address:

Background And Objective: Atrial fibrillation (AF) is a significant cause of life-threatening heart disease due to its potential to lead to stroke and heart failure. Although deep learning-assisted diagnosis of AF based on ECG holds significance in clinical settings, it remains unsatisfactory due to insufficient consideration of noise and redundant features. In this work, we propose a novel multiscale feature-enhanced gating network (MFEG Net) for AF diagnosis.

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Should digoxin immune fab be administered based solely on reported ingested amount in acute digoxin poisoning?

Am J Emerg Med

January 2025

Minnesota Regional Poison Center, Department of Pharmacy, Hennepin Healthcare, Minneapolis, MN, USA; Department of Family Medicine and Biobehavioral Health, University of Minnesota Medical School, Duluth Campus, Duluth, MN, USA. Electronic address:

Acute digoxin poisoning is increasingly uncommon in emergency medicine. Furthermore, controversy exists regarding indications for antidotal digoxin immune fab in acute poisoning. In healthy adults, the fab prescribing information recommends administration based on "known consumption of fatal doses of digoxin: ≥10mg," while many emergency medicine textbooks suggest fab administration be driven by clinical features or potassium concentration.

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Wearable heart rate variability analysis system based on ionic conductive hydrogels.

Talanta

January 2025

Academy of Medical Engineering and Translational Medicine, Medical School, Tianjin University, Tianjin, 300072, China; School of Exercise and Health, Tianjin University of Sport, Tianjin, 300211, China. Electronic address:

Developing a wearable device that can continuously and reliably detect and evaluate heart rate variability (HRV) parameters is critical for the diabetic population with cardiac autonomic neuropathy (CAN). In this work, we proposed a zwitterionic conducting hydrogel that enabled a reliable and comfortable wearable device for the evaluation and detection of the autonomic nervous system (ANS). The hydrogel can achieve a strain of 2003 %, an electrical conductivity of 190 mS/m, and is capable of adhering to a variety of materials, including wood, plastic, and glass.

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