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Time to Percutaneous Drain Placement and Impact on Patient Outcomes.
Surg Infect (Larchmt)
March 2025
Department of Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
Percutaneous drains are a commonly used method of source control for intra-abdominal infections. Increased time to source control has been shown to predict worse outcomes in patients with intra-abdominal infections, but it is unclear whether this relationship is valid when the source control method is percutaneous drainage. We hypothesized that increased time from diagnostic imaging to drain placement would be associated with higher complication rates in a population of patients requiring percutaneous drainage for intra-abdominal, retroperitoneal, or pelvic infectious processes.
View Article and Find Full Text PDFOptimizing Triple-Negative Breast Cancer Therapy via Ultrasound-Enhanced Piezocatalysis for Targeted Chemodrug Release.
Int J Nanomedicine
March 2025
Department of Ultrasound, the Affiliated Hospital of Qingdao University, Qingdao, 266003, People's Republic of China.
Introduction: Triple-negative breast cancer (TNBC) is known for its high malignancy, limited clinical treatment options, and poor chemotherapy outcomes. Although some advancements have been made using nanotechnology-based chemotherapy for TNBC treatment, the controlled and on-demand release of chemotherapeutic drugs at the tumor site remains a challenge.
Methods: We manufactured DOX/BaTiO@cRGD-Lip (DBRL) nanoparticles as an ultrasound (US)-controlled release platform targeting the delivery of Doxorubicin (DOX) for TNBC treatment.
Advances in the detection of biomarkers for ischemic stroke.
Front Neurol
February 2025
Center for Clinical Laboratory, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, Hubei, China.
Ischemic stroke is a leading cause of mortality and morbidity globally. Prompt intervention is essential for arresting disease progression and minimizing central nervous system damage. Although imaging studies play a significant role in diagnosing ischemic stroke, their high costs and limited sensitivity often result in diagnostic and treatment delays.
View Article and Find Full Text PDFSize Matters: Influence of Available Soil Volume on the Root Architecture and Plant Response at Transcriptomic and Metabolomic Levels in Barley.
Plant Cell Environ
March 2025
Department of Soil System Science, Helmholtz Centre for Environmental Research - UFZ, Halle (Saale), Germany.
Pot size is a critical factor in plant growth experiments, influencing root architecture, nutrient uptake, and overall plant development as well as sensing of stress. In controlled environments, variation in pot size can impact phenotypic and molecular outcomes and may bias experimental results. Here, we investigated how pot size affects the root system architecture and molecular responses of two barley genotypes, the landrace BERE and the modern elite CONCERTO, through assessment of shoot and root traits and by using X-ray computed tomography complemented by transcriptomic and metabolomic analyses.
View Article and Find Full Text PDFInnovative optimization of greater omentum imaging report and data system for enhanced risk stratification of omental lesions.
Cancer Imaging
March 2025
Department of Ultrasound, The First Hospital of China Medical University, No. 155, Nanjing North Street, Heping District, Shenyang, Liaoning Province, 110001, China.
Background: In 2020, we introduced the Greater Omentum Imaging-Reporting and Data System (GOI-RADS), a novel classification system related to peritoneal lesions. However, its clinical application remained unvalidated.
Objective: This study aimed to validate GOI-RADS, optimize its parameters for a new grading system, and explore its clinical usefulness.
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