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Intracanal Antibacterial Effects of a Bioceramic Medication Compared With Calcium Hydroxide Pastes in Different Vehicles.
J Endod
November 2024
Postgraduate Program in Dentistry, Iguaçu University (UNIG), Nova Iguaçu, Rio de Janeiro, Brazil; Postgraduate Program in Dentistry, University of Grande Rio (UNIGRANRIO), Rio de Janeiro, Rio de Janeiro, Brazil.
Introduction: The intracanal antibacterial effectiveness of a bioceramic medication was compared with calcium hydroxide pastes in different vehicles.
Methods: Extracted mandibular incisors with a single long oval canal were selected and distributed into 5 groups based on anatomically paired microcomputed tomographic analyses. The root canals were prepared up to an instrument size 35/04 and contaminated for 30 days with a mixed bacterial culture from subgingival biofilm added with Enterococcus faecalis.
Clinical assessment of monolithic zirconia crowns fabricated using an intraoral scanner.
J Dent Res Dent Clin Dent Prospects
September 2024
Prosthodontics Department, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Article Synopsis
- This study evaluated the precision of single-tooth zirconia crowns created with advanced digital technology in a clinical setting involving 30 patients who needed crowns for their posterior teeth.
- The crowns were crafted using a specific method, including deep chamfer preparations and the use of a Trios scanner for digital impressions sent to a lab.
- Results showed that while marginal gaps were slightly larger for molars compared to premolars, overall, the crowns had good fit and most occlusal and proximal contacts were acceptable, indicating high accuracy in crown fabrication.
Multi-site analysis of biosynthetic gene clusters from the periodontitis oral microbiome.
J Med Microbiol
October 2024
Division of Periodontology and Implant Dentistry, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, PR China.
Bacteria significantly influence human health and disease, with bacterial biosynthetic gene clusters (BGCs) being crucial in the microbiome-host and microbe-microbe interactions. Despite extensive research into BGCs within the human gut microbiome, their roles in the oral microbiome are less understood. This pilot study utilizes high-throughput shotgun metagenomic sequencing to examine the oral microbiota in different niches, particularly focusing on the association of BGCs with periodontitis.
View Article and Find Full Text PDFSalivary microbiota reflecting changes in subgingival microbiota.
Microbiol Spectr
November 2024
Department of Periodontology, Institute of Oral Health Science, Ajou University School of Medicine, Suwon, South Korea.
Article Synopsis
- Scientists wanted to see if the germs in saliva could show changes in gum disease after treatment.
- They took samples from healthy people and those with different levels of gum disease, then tested the germs in their saliva and under their gums.
- The results showed that saliva germs can reflect changes in gum health, so it might be used to help check for gum disease in the future.
Impact of smoking habit on the subgingival proteome in patients with periodontitis.
J Periodontol
September 2024
Oral Sciences Research Group, Special Needs Unit, Department of Surgery and Medical-Surgical Specialties, School of Medicine and Dentistry, Universidade de Santiago de Compostela, Health Research Institute of Santiago (IDIS), Santiago de Compostela, Spain.
Background: Few investigations evaluated smoking's impact on the periodontal proteome. Therefore, this study aimed to analyse the influence of tobacco on the overall periodontal proteome and the differential expression of gingival crevicular fluid (GCF) proteins using sequential window acquisition of all theoretical mass spectra (SWATH-MS).
Methods: GCF samples were collected from 40 periodontitis subjects (stages III-IV).
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