Important histochemical observations on the nervous system, obtained in the last years, showed characteristic changes in folic acid and in its main enzyme--dihydrofolate reductase--in the old nerve cells. In neurons, the enzymic activity gradually decreased and folic acid accumulated in ageing. Glial cells preserved or slightly increased the same folate enzyme, but folic acid markedly increased in senescence. Opinions and suggestions bound to these observations are presented.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
folic acid
12
folate metabolism
4
metabolism ageing
4
ageing histochemical
4
histochemical observations
4
observations nervous
4
nervous system
4
system years
4
years characteristic
4
characteristic changes
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!