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Alterations of Gut Microbiome and Serum Metabolome in Coronary Artery Disease Patients Complicated With Non-alcoholic Fatty Liver Disease Are Associated With Adverse Cardiovascular Outcomes.
Front Cardiovasc Med
January 2022
Department of Cardiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Patients suffering from coronary artery disease (CAD) complicated with nonalcoholic fatty liver disease (NAFLD) present worse cardiovascular outcomes than CAD patients without NAFLD. The progression of CAD is recently reported to be associated with gut microbiota and microbe-derived metabolites. However, it remains unclear how the complication of NAFLD will affect gut microbiota and microbe-derived metabolites in CAD patients, and whether or not this interplay is related to the worse cardiovascular outcomes in CAD-NAFLD patients.
View Article and Find Full Text PDFVasodilators for primary Raynaud's phenomenon.
Cochrane Database Syst Rev
May 2021
Department of Rheumatology, Gold Coast University Hospital, Southport, Australia.
Background: Numerous agents have been suggested for the symptomatic treatment of primary Raynaud's phenomenon. Apart from calcium channel blockers, which are considered to be the drugs of choice, evidence of the effects of alternative pharmacological treatments is limited. This is an update of a review first published in 2008.
View Article and Find Full Text PDFRaynaud disease.
J Hand Surg Am
January 2014
Departments of Rheumatology and Orthopedic Surgery, Mayo Clinic, Jacksonville, FL. Electronic address:
Oral vasodilators for primary Raynaud's phenomenon.
Cochrane Database Syst Rev
July 2012
Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK.
Background: Many different drugs have been suggested for the symptomatic treatment of primary Raynaud's phenomenon. Apart from calcium channel blockers, which are considered the drugs of choice, the evidence of the effects of alternative pharmacological treatments is limited. This is an update of a review first published in 2008.
View Article and Find Full Text PDFRaynaud's phenomenon (primary).
BMJ Clin Evid
March 2011
St Joseph's Health Care Rheumatology Centre, London, Ontario, Canada.
Introduction: Raynaud's phenomenon is an episodic vasospasm of the peripheral arteries, causing pallor, followed by cyanosis and redness with pain, and sometimes paraesthesia. On rare occasions it can lead to ulceration of the fingers and toes (and in some cases of the ears or nose). This review focuses on primary (idiopathic) Raynaud's phenomenon, occurring in the absence of an underlying disease.
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