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Bayesian deep learning applied to diabetic retinopathy with uncertainty quantification.
Heliyon
January 2025
Information Technology Department, Technical College of Informatics-Akre, Akre University for Applied Sciences, Kurdistan Regain, Iraq.
Deep Learning (DL) has significantly contributed to the field of medical imaging in recent years, leading to advancements in disease diagnosis and treatment. In the case of Diabetic Retinopathy (DR), DL models have shown high efficacy in tasks such as classification, segmentation, detection, and prediction. However, DL model's opacity and complexity lead to errors in decision-making, particularly in complex cases, making it necessary to estimate the model's uncertainty in predictions.
View Article and Find Full Text PDFBackground: Rearranged during transfection () fusions represent a distinct molecular subset of non-small cell lung cancer (NSCLC) with targeted therapeutic potential. Selpercatinib, a highly selective inhibitor, has demonstrated efficacy in various solid tumors harboring alterations. Here, we present a case highlighting the use and clinical outcomes of selpercatinib in a patient diagnosed with advanced lung adenocarcinoma harboring a fusion.
View Article and Find Full Text PDFMajor change in swine influenza virus diversity in France owing to emergence and widespread dissemination of a newly introduced H1N2 1C genotype in 2020.
Virus Evol
December 2024
ANSES, Ploufragan-Plouzané-Niort Laboratory, Swine Virology Immunology Unit, National Reference Laboratory for Swine Influenza, BP53, Ploufragan 22440, France.
Swine influenza A viruses (swIAVs) are a major cause of respiratory disease in pigs worldwide, presenting significant economic and health risks. These viruses can reassort, creating new strains with varying pathogenicity and cross-species transmissibility. This study aimed to monitor the genetic and antigenic evolution of swIAV in France from 2019 to 2022.
View Article and Find Full Text PDFRoux-en-Y Intussusception: A Case Report.
Cureus
January 2025
General Surgery, Tampa General Hospital Brooksville, Brooksville, USA.
Roux-en-Y gastric bypass (RYGB) is a bariatric surgical procedure commonly performed in adults to treat severe obesity. While RYGB is generally safe, it occasionally leads to rare but significant complications, including intussusception, a form of bowel obstruction caused by the invagination of an intestine segment from the proximal to the adjacent distal portion. We report a case of intussusception in a 74-year-old female patient who underwent RYGB 12 years prior.
View Article and Find Full Text PDFThe Role of Endoscopic Cyclophotocoagulation as a Primary Alternative Treatment for Patients at Risk of Ocular Hypotony: A Case Report.
Cureus
January 2025
Ophthalmology, Royal Free Hospital, London, GBR.
Endoscopic cyclophotocoagulation (ECP) offers a viable alternative for managing advanced primary open-angle glaucoma (POAG) in patients at risk of ocular hypotony. We describe a case of a successful outcome with ECP in a patient who developed ocular hypotony secondary to Preserflo surgery. A 93-year-old South Asian male experienced significant visual field deterioration and ocular hypotony following Preserflo surgery on the left eye, complicated by a severe cough from COVID-19.
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