The Authors have been evaluated the behaviour of serum ferritin in 16 patients with breast cancer. In all of the cases the serum ferritin values were significantly higher, compared with those found in 11 normal control subjects. Of particular interest was the reduction of serum ferritin in most of the patients who had undergone polychemotherapy with CMF. The results agree with the observations of various Authors as far as high levels of serum ferritin in course of breast cancer are concerned. Moreover it can be pointed out that the serum ferritin evaluation can represent a monitoring marker for the evaluation of the evolution of this disease.

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