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Background: 2-(Thiocyanomethylthio)benzothiazole (TCMTB) is a fungicide product widely used in the leather industry, particularly since the 1990s. However, reports of allergic contact dermatitis triggered by this chemical are scarce.

Objectives: To investigate three cases of dermatitis following contact with leather products, possibly related to TCMTB.

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Interference of the positioning of nickel, chromium and cobalt in the results of patch tests.

An Bras Dermatol

December 2024

Department of Medicine, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brazil.

Background: The positioning of substances, which are co-sensitizers and/or with a tendency to cross-react, is not considered in the technique when applying patch tests (PT).

Objective: To investigate the interference of the positioning of nickel (Ni), chromium (Cr) and cobalt (Co) in patch tests (PT) results, when applied close or distant from each other.

Methods: PT were performed in patients suspected of allergic contact dermatitis (ACD), using the standard battery (SB), with substances showing a tendency towards cross-react and co-sensitizers applied far apart, and an additional battery (AB) with the metals placed close to each other.

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The study investigates the concentration of heavy metals in various lipsticks sold in Ghana and assesses the potential health risks associated with their use. A total of 12 lipstick samples were analyzed using an X-ray fluorescence (XRF) analyzer for metals, including chromium (Cr), manganese (Mn), nickel (Ni), copper (Cu), cadmium (Cd), and lead (Pb). The findings revealed that Cr levels ranged from below detection limits to 2554.

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Introduction: Traces of hexavalent chromium, Cr(VI), are a major concern for skin contact with Cr-tanned leather. Current extraction methods (ISO 17075-1:2017) for Cr(VI) testing do not necessarily reflect the true potential of surface-formed Cr(VI), as extracted concentrations are dependent on previous storage and atmospheric conditions.

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