Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0090-1229(81)90141-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Nanoparticle-assisted PCR: fundamentals, mechanisms, and forensic implications.
Int J Legal Med
January 2025
Biological and Life Sciences, School of Arts and Sciences, Ahmedabad University, Central Campus, Navrangpura, Ahmedabad, Gujarat, India.
Polymerase Chain Reaction (PCR) has transformed forensic DNA analysis but is still limited when dealing with compromised trace or inhibitor-containing samples. Nanotechnology has been integrated into nanoPCR (nanoparticle-assisted PCR) to overcome these obstacles. Nanomaterials improve PCR sensitivity, selectivity, and efficiency.
View Article and Find Full Text PDFPTPN23-dependent activation of PI3KC2α is a therapeutic vulnerability of BRAF-mutant cancers.
J Exp Med
March 2025
Institute of Cancer Research, Shenzhen Bay Laboratory , Shenzhen, China.
BRAF mutations drive initiation and progression of various tumors. While BRAF inhibitors are effective in BRAF-mutant melanoma patients, intrinsic or acquired resistance to these therapies is common. Here, we identify non-receptor-type protein tyrosine phosphatase 23 (PTPN23) as an alternative effective target in BRAF-mutant cancer cells.
View Article and Find Full Text PDFanti-diabetic potential of medicinal herbs commonly used in the Ayurvedic system of Sri Lanka with comprehensive metabolite profiling of using GC-MS and LC-HRMS.
Nat Prod Res
January 2025
Nutritional Biochemistry Program, National Institute of Fundamental Studies, Kandy, Sri Lanka.
This study assessed the anti-diabetic potential and bioactive constituents of ten Sri Lankan medicinal herbs. Initial screening of aqueous extracts for starch-digesting enzyme inhibition prioritised three plants with notable activity ( ≤ 0.05), for further assessment using methanolic extracts: (PE), (CA), and (HI).
View Article and Find Full Text PDFKnowledgedriven design of boron-based catalysts for oxidative dehydrogenation of propane.
Phys Chem Chem Phys
January 2025
State Key Laboratory of Fine Chemicals, Liaoning Key Laboratory for Catalytic Conversion of Carbon Resources, School of Chemistry, Dalian University of Technology, Dalian 116024, China.
Metal-free boron-based materials exhibit remarkable performance in oxidative dehydrogenation of propane (ODHP). Rational design of boron-based catalysts requires a systematic understanding of the underlying mechanisms to constitute a knowledge base. This work provides a comprehensive view of the reaction mechanism of the boron-based ODH reaction and discusses the key features of the reaction systems, including the inhibition of deep oxidation, high olefin selectivity, and the role of water in the ODHP reaction.
View Article and Find Full Text PDFMyelodysplastic syndromes (MDS) are age-related diseases characterized by bone marrow (BM) dysfunction and an increased risk of developing acute leukemia. While there is growing evidence highlighting the crucial role of the BM microenvironment (BMME) in MDS, the specific influence of inflammation on BMME changes, as well as the potential benefits of targeting cytokines therapeutically, remain to be elucidated. We previously found interleukin-1 (IL-1) to be a driver of aging phenotypes of BMME and hematopoietic stem and progenitor cells (HSPCs).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!