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Abnormal neural circuits and altered brain network topological properties in patients with persistent postural-perceptual dizziness.
Commun Biol
January 2025
Department of Neurology, Peking University First Hospital, Beijing, People's Republic of China.
Persistent Postural-Perceptual Dizziness (PPPD) is a common cause of chronic vestibular syndrome. Although previous studies have identified central abnormalities in PPPD, the specific neural circuits and the alterations in brain network topological properties, and their association with dizziness and postural instability in PPPD remain unclear. This study includes 30 PPPD patients and 30 healthy controls.
View Article and Find Full Text PDFMechanism of microscopic behind the influence of stress loading on gas adsorption by coal.
Sci Rep
January 2025
College of Environment and Bioengineering, Henan University of Engineering, Zhengzhou, 451191, China.
This study aims to explore the mechanism behind the influence of stress on gas adsorption by coal during deep mining and improve the accuracy of gas disaster prevention and control. To achieve this aim, thermodynamic analysis was conducted on the process of gas adsorption by loaded coal, and modified thermodynamic model proposed by previous scholars. It is found that stress plays an important role in gas adsorption by coal.
View Article and Find Full Text PDFElectrophysiological signatures of the effect of context on exploration: Greater attentional and learning signals when exploration is costly.
Brain Res
January 2025
Department of Computing Science, University of Alberta Edmonton Alberta Canada; Alberta Machine Intelligence Institute Edmonton Alberta Canada; Canada Institute for Advanced Research (CIFAR) AI Chair, Canada.
Humans are excellent at modifying our behaviour depending on context. For example, humans will change how they explore when losses are possible compared to when they are not possible. However, it remains unclear what specific cognitive and neural processes are modulated when exploring in different contexts.
View Article and Find Full Text PDFMolecular mechanism of protein-lipid interactions in steamed egg gelation and deterioration: A quantitative proteomic study.
Int J Biol Macromol
January 2025
Institute for Egg Science and Technology, School of Food and Biological Engineering, Chengdu University, No. 2025 Chengluo Avenue, Chengdu 610106, China. Electronic address:
Steamed egg (SE), a traditional egg dish, exhibits steaming time-dependent textural properties. This study investigated the molecular mechanisms underlying SE gel formation and deterioration through quantitative proteomics combined with physicochemical characterization. Results showed optimal gel formation at 11 min steaming, while prolonged steaming (23 min) led to gel cracking and sensory deterioration.
View Article and Find Full Text PDFLabel-free quantitative imaging of conjunctival goblet cells.
Ocul Surf
January 2025
Division of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea, 37673; Department of Mechanical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea, 37673. Electronic address:
Purpose: To introduce and validate quantitative oblique back-illumination microscopy (qOBM) as a label-free, high-contrast imaging technique for visualizing conjunctival goblet cells (GCs) and assessing their functional changes.
Methods: qOBM was developed in conjunction with moxifloxacin-based fluorescence microscopy (MBFM), which was used for validating GC imaging. Initial validation was conducted with polystyrene beads, followed by testing on normal mouse conjunctiva under both ex-vivo and in-vivo conditions.
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