Non-symbolic axial movements were examined and compared to oral and limb movements in a group of 60 aphasic patients (15 of each major subgroup) with exclusively left-sided brain damage. The contention in the literature that axial movements are preserved in patients with ideomotor limb apraxia was not confirmed.
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http://dx.doi.org/10.1136/jnnp.45.12.1125 | DOI Listing |
Diagnostics (Basel)
February 2025
Interventional Radiology Department, AORN "A. Cardarelli", 80131 Naples, Italy.
Deep vein thrombosis (DVT) of the lower extremities, as part of venous thromboembolism disorder, is the third leading cause of acute cardiovascular syndrome after heart attack and stroke. It can result in disability due to pulmonary embolism (PE) and post-thrombotic syndrome (PTS), particularly in cases where the thrombosis extends to the iliofemoral veins. Anticoagulation therapy is effective in preventing thrombus propagation and embolism but may not be sufficient for thrombus degradation and venous patency restoration.
View Article and Find Full Text PDFProg Neurobiol
March 2025
Department of Medicine and Surgery (DIMEC), Neuroscience Unit, University of Parma, Italy. Electronic address:
Classically, the insula is considered an associative multisensory cortex where emotional awareness emerges through the integration of interoceptive and exteroceptive information, along with autonomic regulation. However, since early intracortical microstimulation (ICMS) studies, the insular cortex has also been conceived as a mosaic of anatomo-functional sectors processing various types of sensory information to generate specific overt behaviors. Based on this, the insula has been subdivided into distinct functional fields: an anterior field associated with oroalimentary behaviors, a middle field involved dorsally in hand movements and ventrally in emotional reactions, and a posterior field engaged in axial and proximal movements.
View Article and Find Full Text PDFSemin Arthritis Rheum
March 2025
Rheumatology Department, Reina Sofia University Hospital, 14005 Córdoba, Spain; Maimonides Biomedical Research Institute of Cordoba (IMIBIC), 14005 Córdoba, Spain; Medical and Surgical Sciences Department, University of Cordoba, 14005 Córdoba, Spain.
Objective: This study aimed to evaluate the association of cervical and lumbar mobility with functional ability in patients with axial spondyloarthritis (axSpA) using an inertial measurement unit (IMU) sensor system, as well as the influence of disease duration on this association.
Methods: This cross-sectional study included 156 patients with axSpA from the Córdoba axSpA Task Force Registry and Outcomes (CASTRO) registry. Spinal mobility was assessed with the IMU system and functional ability was measured using the Bath Ankylosing Spondylitis Functional Index (BASFI).
Eur J Neurosci
March 2025
Neurology Clinic, Etlik City Hospital, Ankara, Turkey.
There are still debates regarding the pathophysiology of freezing of gait (FOG) in Parkinson's disease (PD). This study aims to investigate the potential contribution of the nonmotor symptoms in the pathophysiology of FOG. This was a cross-sectional observational cohort study where we enrolled all consecutive PD patients who applied to our movement disorders outpatient clinics at Etlik City Hospital, Ankara, Turkey, between January 2024 and August 2024.
View Article and Find Full Text PDFNeurobiol Dis
March 2025
Department of Neurology, The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, China. Electronic address:
Objective: The loss of locus coeruleus (LC)-norepinephrine system may contribute to freezing of gait (FOG) in Parkinson's disease (PD), but free-water (FW) imaging has not been applied to investigate LC microstructural degeneration in FOG. This study was to investigate the role of the LC-norepinephrine system in FOG pathophysiology using FW imaging and resting-state functional magnetic resonance imaging.
Methods: FW metrics of LC were analyzed in 52 healthy controls, 79 PD patients without FOG (Non-FOG), and 110 PD patients with FOG (48 "Off-period" FOG and 62 "Levodopa unresponsive" FOG).
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