Establishment of xenografts or cell culture lines in which the alpha-fetoprotein (AFP) characteristic of clinical hepatoblastoma persists have been difficult. The serially transplantable strain (HB-3) of highly AFP-producing hepatoblastoma was successfully established in nude mice. And a highly AFP producing cell line (c-HB-3) is easily obtained by HB-3. This strain and line give us an ideal experimental model of hepatoblastoma in vivo and in vitro.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/1097-0142(19820701)50:1<97::aid-cncr2820500118>3.0.co;2-4 | DOI Listing |
Publication Analysis
Top Keywords
experimental model
8
establishment experimental
4
model human
4
hepatoblastoma
4
human hepatoblastoma
4
hepatoblastoma establishment
4
establishment xenografts
4
xenografts cell
4
cell culture
4
culture lines
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!