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Successful conversion surgery after comprehensive therapy in a patient with MSI-H but pMMR metastatic gastric mixed adenoneuroendocrine carcinoma: a case report and literature review.
Front Oncol
December 2024
Department of Gastroenterology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Gastric mixed adenoneuroendocrine carcinoma (MANEC) is a rare and highly aggressive malignancy characterized by both exocrine and neuroendocrine components. Treatment options for metastatic cases are limited, with typical therapeutic approaches involving a combination of chemotherapy and immunotherapy. A 68-year-old male with metastatic gastric MANEC was treated with targeted therapy, immunotherapy, and chemotherapy, including S-1, apatinib, cadonilimab, and paclitaxel.
View Article and Find Full Text PDFCase report: Splenic infarction secondary to asymptomatic atrial fibrillation, necessitating splenectomy.
Int J Surg Case Rep
January 2025
Department of Hepatobiliary Surgery, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China. Electronic address:
Introduction: Splenic infarction caused by thrombi rarely causes abdominal pain in acute abdomen patients. This report describes a case of splenic infarction caused by thrombus detachment due to paroxysmal atrial fibrillation, which was successfully treated and discharged from the hospital.
Case Presentation: A 52-year-old woman walked into the emergency room with left upper abdominal pain, nausea, and vomiting 12 h prior.
Left-sided portal hypertension caused by a solid pseudopapillary neoplasm of pancreas tail: a pediatric case report.
Surg Case Rep
November 2024
Department of Diagnostic Pathology, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Article Synopsis
- Solid pseudopapillary neoplasm (SPN) is a low-grade malignant tumor mostly seen in pediatric cases, where spleen preservation during surgery is critical to prevent infection, though complications like left-sided portal hypertension (LSPH) can complicate this.
- A 12-year-old girl diagnosed with SPN had symptoms like abdominal pain and anemia, and imaging revealed a mass in her pancreas along with signs of LSPH, prompting a surgery that initially aimed to preserve the spleen.
- Despite the initial surgery, the patient faced ongoing abdominal pain due to LSPH-related issues, leading to a splenectomy, which resolved her pain and showed no recurrence after eight years.
Hypovascular insulinoma with reduced microvessel density on histopathology: a case report.
Diabetol Int
October 2024
Department of Diabetes, Endocrinology and Metabolism and Department of Rheumatology and Clinical Immunology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194 Japan.
Article Synopsis
- A 41-year-old man suspected of having insulinoma underwent various imaging tests, revealing a hypovascular tumor in the pancreas, which was ultimately diagnosed as a Grade 1 PanNET following surgery and pathology.
- The tumor's low microvessel density (MVD) of 3.9% contributed to inconclusive imaging results, highlighting the need for thorough preoperative evaluations in cases of hypovascular PanNETs to ensure accurate diagnosis and treatment.
Case Report: Reflection on a case of splenic abscess in a child.
Front Pediatr
September 2024
Department of Infectious Disease Department, The Third People's Hospital of Chengdu, Chengdu, China.
Splenic abscesses (SA), especially in children, are rare in clinical practice. The missed diagnosis rate of SA is high and the probability of rapidly diagnosing it is relatively low due to its low incidence rate and the presence of non-specific clinical symptoms and imaging manifestations. Antibiotics are the primary treatment for SA; however, ultrasound-guided percutaneous puncture suction or drainage, and splenectomy are other effective treatment strategies.
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