The first example of a duplication involving the human beta-like globin genes has been characterised in DNA from a native of Vanuatu. Restriction endonuclease mapping has shown that a 5 kb insert of DNA in the gamma-delta-beta gene cluster is due to duplication of the Ggamma-globin gene and results in a new rearrangement 5'-epsilon-Ggamma-Ggamma-Agamma-delta-beta-3'.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327636 | PMC |
| http://dx.doi.org/10.1093/nar/9.24.6723 | DOI Listing |
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