The authors describe 6 cases of the Peuzt-Jeghers syndrome found in one family. The clinical, radiological, endoscopical, laboratorial and surgical points of view are discussed. Through these different diagnostic methods polyps in the esophagus (1 case), stomach (2 cases), small intestine (2 cases) and colon (4 cases) were identified. Of these patients the two with polyps in the small intestine were operated on for intestinal occlusion. In this paper the authors discuss, and doubt, the reported rarity of this syndrome, as well as the true frequency of distribution in the digestive tract.

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