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A Reconfigurable, Nonlinear, Low-Power, VCO-Based ADC for Neural Recording Applications.

Sensors (Basel)

September 2024

Dipartimento di Ingegneria Navale, Elettrica, Elettronica e delle Telecomunicazioni (DITEN), University of Genoa, 16145 Genoa, Italy.

Neural recording systems play a crucial role in comprehending the intricacies of the brain and advancing treatments for neurological disorders. Within these systems, the analog-to-digital converter (ADC) serves as a fundamental component, converting the electrical signals from the brain into digital data that can be further processed and analyzed by computing units. This research introduces a novel nonlinear ADC designed specifically for spike sorting in biomedical applications.

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Continuous-time asynchronous data converters namely, analog-to-digital converters and analog-to-time converters, can be beneficial for certain types of applications, such as, processing of biological signals with sparse information. A particular case of these converters is the integrate-and-fire converter (IFC) that is inspired by the neural system. If it is possible to develop a standard-cell-based (SCB) IFC circuit to perform well in advanced technology nodes, it will benefit from the simplicity of SCB circuit designs and can be implemented in widely available field-programmable gate arrays (FPGAs).

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This paper presents a 10-channel, 120 nW/channel, reconfigurable capacitance-to-digital converter (CDC) enabling sub- μW wearable sensing applications. The proposed multi-channel architecture supports 10 channels with a shared reconfigurable 6-bit differential analog-to-digital converter (ADC). The reconfigurable nature of the CDC enables adaptive sensing range and sensing speed based on the target application.

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Intan Technologies' integrated circuits (ICs) are valuable tools for neurophysiological data acquisition, providing signal amplification, filtering, and digitization from many channels (up to 64 channels/chip) at high sampling rates (up to 30 kSPS) within a compact package (⩽9× 7 mm). However, we found that the analog-to-digital converters (ADCs) in the Intan RHD2000 series ICs can produce artifacts in recorded signals. Here, we examine the effects of these ADC artifacts on neural signal quality and describe a method to detect them in recorded data.

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Article Synopsis
  • * This study presents a new strategy using analog beamforming with reconfigurable intelligent surfaces (RIS) to enhance interference mitigation in downlink transmissions of hybrid analog-digital mmWave systems.
  • * The researchers provide formulas for assessing performance rates and demonstrate that their method, which employs low-resolution converters, is energy-efficient and superior to other existing methods based on simulation results.
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