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Neonatal sepsis, a severe infection in newborns, remains one of the leading causes of morbidity and mortality among preterm infants. This study aimed to investigate the distribution of pathogens responsible for early-onset sepsis (EOS) and late-onset sepsis (LOS), the annual variability of pathogens responsible for each type of infection, and potential trends in their profiles in preterm infants from a tertiary care neonatal intensive care unit over a ten-year period. We analyzed 177 episodes of confirmed bloodstream infection between 1 January 2014 and 31 December 2023.

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Background: We analyzed the clinical distribution and the antibiotic susceptibility of pathogens for catheter-related blood stream infection (CRBSI) in the hospital retrospectively.

Methods: The clinical information and pathogens associated with CRBSI were collected from the Microbiology Laboratory of the hospital retrospectively from January 2017 to December 2021. Identification and the antibiotic susceptibility test (AST) were carried out with VITEK-2 Compact.

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Article Synopsis
  • - The study evaluated the presence of Methicillin-Resistant Staphylococcus (MRS) on the skin and in the nasal cavities of healthcare workers (HCWs), finding a significant number were carriers of these resistant bacteria, particularly MRSA among male HCWs and MRSE among nurses.
  • - Swab samples collected from HCWs were cultured to identify MRS and assess their susceptibility to antibiotics, showing a high incidence of methicillin resistance particularly in doctors and nurses.
  • - The findings indicated the need for improved preventive measures against the spread of these infections in hospitals, with vancomycin suggested as a highly effective treatment for MRSA and MRSE infections.
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Background: This study aimed to analyze the distribution of multidrug-resistant (MDR) organisms (MDROs) in patients with diabetic foot ulcers (DFUs) and to identify risk factors for MDRO infections.

Methods: Patients hospitalized with DFUs were enrolled, and ulcer swabs were cultured for bacterial identification and antibiotic susceptibility testing. Hematology and blood biochemistry were also assessed.

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Article Synopsis
  • This study conducted in Rabigh City, Saudi Arabia aimed to identify antimicrobial resistance (AMR) in common pathogenic bacteria within a healthcare facility over a six-month period.
  • Out of 1,933 patient samples, 11.1% showed bacterial growth, with a higher prevalence in patients over 50 years old; the majority were Gram-negative bacteria like E. coli and K. pneumoniae.
  • The findings reveal significant resistance among isolated bacteria, particularly with K. pneumoniae showing increased resistance to carbapenem antibiotics, emphasizing the need for ongoing monitoring of AMR in healthcare environments.
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