A new antibiotic, substance SF-1771, has been isolated for the fermentation broth of Streptomyces toyocaensis SF-1771. The antibiotic is highly active against Gram-positive and -negative bacteria and effective against sarcoma 180 cells of ascites type in mice. It belonged to the phleomycin-bleomycin group antibiotics, but has been differentiated from the known antibiotics by the physiochemical properties, chromatographic behaviors and amino acid analysis.
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http://dx.doi.org/10.7164/antibiotics.33.1236 | DOI Listing |
A new antibiotic, substance SF-1771, has been isolated for the fermentation broth of Streptomyces toyocaensis SF-1771. The antibiotic is highly active against Gram-positive and -negative bacteria and effective against sarcoma 180 cells of ascites type in mice. It belonged to the phleomycin-bleomycin group antibiotics, but has been differentiated from the known antibiotics by the physiochemical properties, chromatographic behaviors and amino acid analysis.
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