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Machine learning-enhanced detection of chlorpyrifos using molecularly imprinted polymer-coated optical fibers.
Talanta
January 2025
Department of Physics, Institute of Science, Banaras Hindu University, Varanasi, 221005, India. Electronic address:
This paper explores the use of large core declad optical fibers coated with molecularly imprinted polymers for chlorpyrifos detection, a key marker of organophosphate pesticides. The performance of sensor is evaluated using artificial neural networks and principal component analysis. By varying the declad length, the performance of molecularly imprinted polymer-coated fibers is compared to uncoated fibers, and both are used to identify commercial and pure samples of chlorpyrifos pesticides.
View Article and Find Full Text PDFEco-friendly green synthesis of silver nanoparticles from guajava leaves extract for controlling organophosphorus pesticides hazards, characterization, and in-vivo toxicity assessment.
BMC Pharmacol Toxicol
December 2024
Plant Protection Department, Faculty of Agriculture, Beni-Suef University, Beni-Suef, Egypt.
This study explores an eco-friendly approach to mitigate risks associated with organophosphorus insecticides, particularly Chlorpyrifos, by synthesizing silver nanoparticles (AgNPs) using Psidium guajava leaf extract and preparing a nanocomposite (AgNPs/S18) with Chlorpyrifos pesticide. The green-synthesized AgNPs and AgNPs/S18 nanocomposite were characterized using various analytical techniques, confirming the successful synthesis of AgNPs with an average size of 37 nm and forming a stable nanocomposite. Antibacterial assays demonstrated significant activity against Staphylococcus aureus, with AgNPs showing an 87.
View Article and Find Full Text PDFHuman-Induced Pluripotent Stem Cell-Derived Neural Organoids as a Novel In Vitro Platform for Developmental Neurotoxicity Assessment.
Int J Mol Sci
November 2024
Environmental Health and Prevention Research Unit, Yokohama University of Pharmacy, 601 Matano, Totsuka, Yokohama 245-0066, Japan.
There has been a recent drive to replace in vivo studies with in vitro studies in the field of toxicity testing. Therefore, instead of conventional animal or planar cell culture models, there is an urgent need for in vitro systems whose conditions can be strictly controlled, including cell-cell interactions and sensitivity to low doses of chemicals. Neural organoids generated from human-induced pluripotent stem cells (iPSCs) are a promising in vitro platform for modeling human brain development.
View Article and Find Full Text PDFResistance intensity test (RIT): a novel bioassay for quantifying the level of acaricide resistance in Rhipicephalus microplus ticks.
Parasit Vectors
November 2024
Instituto de Pesquisas Veterinárias Desidério Finamor, Estrada Do Conde, 6000, Eldorado Do Sul, RS, 92990-000, Brazil.
Background: One bioassay for detecting acaricide resistance in livestock ticks is the adult immersion test (AIT), wherein engorged ticks are briefly immersed into a solution of a particular acaricidal compound and examined for mortality, their egg-laying capacity and offspring hatchability in vitro. Usually, the recommended label dose or an established discriminating dose of an acaricide is used to determine high mortality (≥ 95%) of susceptible tick strains. Such a test intends to detect the presence of resistance in a tick population.
View Article and Find Full Text PDFExposure to organophosphate insecticides induces behavioral changes and acetylcholinesterase inhibition in Apis mellifera.
Ecotoxicol Environ Saf
November 2024
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
European honey bee (Apis mellifera L.) is an essential pollinator that contributes significantly to the global ecosystem and agricultural productivity. However, their population has been facing unprecedented threats, primarily due to their exposure to various pesticides, including organophosphates.
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