Among 233 patients with occlusion of the central retinal vein studied for 3 to 12 years 89 had no glaucoma, 77 had primary glaucoma alone and 67 had thrombotic glaucoma. In those with thrombotic glaucoma the intraocular pressure and its postural change in the affected eye never decreased and sometimes increased after the instillation of pilocarpine. Glaucoma secondary to occlusion of the central retinal vein always appeared suddenly. For 1 to 2 days blood could be seen in the angle of the anterior chamber. At the same time the intraocular pressure rapidly increased and the visual acuity fell. The anterior chamber was never flat. This acute stage continued for as little as several days to as long as 1.5 months. During the chronic stage the eye was blind and the intraocular pressure remained high, but there was no pain and the eye did not appear to be irritated. A mass of newly formed blood vessels was present on the iris.
Download full-text PDF |
Source |
---|
J Int Med Res
December 2024
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Objective: Retinal vein occlusion (RVO) leads to visual impairment, and risk factors may include glaucoma. Although some studies suggest a relationship between glaucoma and RVO, it is unknown whether this association is causal. We performed Mendelian randomization (MR) analyses to evaluate the causal contribution to RVO of five genetically predicted glaucoma conditions.
View Article and Find Full Text PDFAs retinal vein occlusion is such a complex systemic disease, its underlying risk profile should be narrowed down individually. Ophthalmologists should always rule out glaucoma or ocular hypertension while also screening the patient for systemic vascular diseases or risk factors in particular. Intravitreally applied medication (VEGF inhibitors or steroids) and laser coagulation (focal or panretinal) or a combination thereof can be considered to treat such retinal anomalies.
View Article and Find Full Text PDFEur J Med Res
November 2024
Department of Ophthalmology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, 366 Taihu Road, Hailing District, Taizhou, 225300, Jiangsu, China.
Int J Biochem Cell Biol
December 2024
Department of Health Sciences, Biochemistry Laboratory, University of Milan, Via A. di Rudinì 8, Milan, Italy. Electronic address:
Mitomycin C as well as other antiproliferative drugs are off-label agents widely used to prevent the failure of glaucoma surgery due to activation of Tenon's fibroblasts and the ensuing excessive subconjunctival scarring. Though efficacious, these treatments are associated with some severe long-term complications, so it is crucial to investigate less cytotoxic compounds as adjuvant therapy in glaucoma surgery. The aim of this study was to evaluate the effect and potential cytotoxicity of Myriocin, a natural sphingolipid synthesis inhibitor, on TGF-β1-induced myofibroblasts transformation of human dermal fibroblasts.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
October 2024
Department of Ophthalmology and Visual Sciences, West Virginia University School of Medicine, Morgantown, WV, 26505, USA.
Purpose: To report the rates and risk factors for layered hyphemas after goniotomy (PG) and trabecular bypass stent (PTBS) surgery combined with phacoemulsification.
Methods: Patient data was obtained using a retrospective chart review from adult patients (18 years of age or older) undergoing either PG or PTBS at the West Virginia University Eye Institute between 2013 and 2023. Generalized estimating equations were used to identify significant predictors of layered hyphema on post-operative day one.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!