AI Article Synopsis
- Adult thymectomy stops the formation of suppressor T cells, which are crucial for immune regulation.
- Despite the lack of suppressor T cells, the body can still achieve immunologic tolerance to the same antigens.
- This indicates that immune suppression and immune tolerance operate through different cellular mechanisms.
Article Abstract
Adult thymectomy prevents the development of suppressor T cells without impairing the induction of immunologic tolerance to the same antigenic determinant. This finding demonstrates that the cellular mechanisms underlying immune suppression and immune tolerance are different.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185794 | PMC |
| http://dx.doi.org/10.1084/jem.151.3.743 | DOI Listing |
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