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Feasibility and impact of sentinel lymph node biopsy in patients affected by ano-rectal melanoma.
Tech Coloproctol
January 2025
Department of Surgical Sciences, University of Turin, Turin, Italy.
Introduction: Anorectal melanoma (ARM) is rare and highly lethal neoplasm. It has a poorer prognosis compared with cutaneous ones. Sentinel lymph node biopsy (SLNB) has become the preferred method of nodal staging method for cutaneous melanoma.
View Article and Find Full Text PDFBoron-Doped Nano Hydroxyapatite Grafts for Bone Regeneration in Rat Mandibular Defects.
Biol Trace Elem Res
December 2024
Sivas Cumhuriyet University, Sivas, Türkiye.
The aim of this study was to evaluate the potential effects of boron-doped nano hydroxyapatite grafts on craniofacial bone regeneration in critical bone defects in the mandibular corpus of rats, in terms of scintigraphic and histopathological aspects. Forty Wistar albino rats, with an average weight of 200-220 g, aged 16-18 weeks, and all male, were used in the study. The rats were randomly assigned to five groups, each containing 8 rats, as follows: group C1 (no procedure applied to the mandible), group C2 (surgical defect created in the mandible but no treatment applied), group nHA (nano hydroxyapatite applied to the surgical defect area), group nHA + B1 (nano hydroxyapatite + 1% boron applied to the surgical defect area), and group nHA + B2 (nano hydroxyapatite + 2% boron applied to the surgical defect area).
View Article and Find Full Text PDFPre-symptomatic scintigraphic and genetic cascade screening in cardiac transthyretin amyloidosis.
Eur J Nucl Med Mol Imaging
November 2024
Jagiellonian University Medical College, Department of Cardiac and Vascular Diseases, Institute of Cardiology, St. John Paul II Hospital, Pradnicka 80, 31-202, Krakow, Poland.
Purpose: While early diagnosis is crucial, as new treatments can significantly slow the progression of the disease, there is growing evidence on the application of novel imaging techniques for detecting transthyretin amyloidosis (ATTR) in pre-symptomatic stages. This study aimed to evaluate the utility of pre-symptomatic scintigraphic imaging cascade screening for early detection of ATTR.
Methods: During the period from 2020 to 2024, we conducted a prospective study that enrolled 100 consecutive adults.
The Utility of Baseline Characteristics and [I]MIBG Cardiac Adrenergic System Scintigraphy in Qualifying Patients with Post-Infarction Heart Failure for Implantable Cardioverter-Defibrillator (ICD) Placement.
J Clin Med
October 2024
Department of Congenital Heart Diseases, National Institute of Cardiology, 04-628 Warsaw, Poland.
Post-infarction heart failure with reduced ejection fraction (HFrEF) patients often face persistent risks of sudden cardiac arrest leading to sudden cardiac death. While implanting a cardioverter-defibrillator (ICD) can enhance prognosis, complications and costs limit its widespread use. Current patient qualification criteria, relying on imperfect parameters, require refinement.
View Article and Find Full Text PDFVascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study.
Medicina (Kaunas)
October 2024
Faculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkey.
Article Synopsis
- The study focuses on tendon injuries in complex wounds of the hand and lower extremities, exploring how different types of adipofascial tissue flaps affect healing and functional recovery.
- It compares vascularised versus nonvascularised adipofascial flaps using Wistar Albino rats, assessing healing through scintigraphic evaluations and histopathological analysis.
- Results indicate that vascularised flaps promote faster healing while pedicle-free flaps also aid tendon recovery without complications, providing insights for improving tendon repair techniques in reconstructive surgery.
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