A report is given about the opportunity and the advantages of combining the traditional scheme for the study of the pathological immunoglobulins with the analysis of the uncoupling of the bow of precipitation against IgG and the isolation of the pathological immunoglobulin through a diluition of the serum such as to bring the fraction electrophoretically dispersed to not detectable levels and make it detectable the monoclonae portion electrophoretically homogeneous.

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