The saccharin clearance time technique was used to determine the effect upon nasal mucociliary transport of sine wave oscillations. Nasal air was oscillated at 8 Hz, 14 Hz, and 20 Hz by a loudspeaker attached to a nasal mask. Mucociliary transport was significantly increased at all frequencies with an overall mean rise of 161%. Because sine waves have zero mean pressure and flow, the improvement is more likely to be caused by changes in mucus viscoelasticity or ciliary function rather than by a direct physical effect on mucus velocity. This simple and comfortable technique may have practical application in patients with overproduction or retention of mucus within the nasal passages or intrathoracic airways.
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