Conditions have first been developed for the preparation of erythrocyte immunoglobulin diagnostic preparation of erythrocyte immunoglobulin diagnostic preparation for HFRS virus which permits express detection of the specific virus antigen in suspensions of the lung tissue of rodents by means of the indirect hemagglutination test (IHA) and laboratory diagnosis of the infection in humans by means of antibody detection by the indirect hemagglutination-inhibition test (IHAI). The IHA test is as sensitive as immunofluorescence, while the sensitivity of the IHAI test is not inferior to that of immunofluorescence but is higher than that of RIA.
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Vet Immunol Immunopathol
January 2025
Department of Veterinary and Animal Sciences, University of Copenhagen, Dyrlægevej 88, Frederiksberg C 1870, Denmark.
Newcastle disease (ND) is a notifiable avian disease responsible for several panzootics, which has resulted in the establishment of mandatory vaccination programs against the virus in several countries including Denmark. This study compared the immune response elicited in layers by the standard vaccination program for ND of a Danish commercial egg production facility with a simplified version of the vaccination program. A commercial flock of layers was followed for 77 weeks from hatching to culling.
View Article and Find Full Text PDFBraz J Vet Med
January 2025
Veterinarian, Neurology Department, AniCura Istituto Veterinario di Novara, Granozzo con Monticello, Novara, Italy.
An 11-year-old male Bengal tiger () was referred for a 2-week history of ambulatory tetraparesis, generalized ataxia, and hypermetric gait, associated with mild right head tilt and spontaneous proprioceptive deficit on the right forelimb. Neuroanatomical localization was C1-C5 myelopathy; cerebellum-vestibular system involvement was also considered. Hematology and serum biochemistry were unremarkable, although serum vitamin A (0.
View Article and Find Full Text PDFPLoS One
January 2025
Faculty of Veterinary Science, The Monitoring and Surveillance Center for Zoonotic Diseases in Wildlife and Exotic Animals, Mahidol University, Nakhon Pathom, Thailand.
Crocodilians are susceptible to a range of virus infection including influenza A virus (IAV). However, little is known about the ecology and epidemiology of IAV in crocodile species. This study aimed to investigate IAV infection in farmed Siamese crocodiles in central Thailand.
View Article and Find Full Text PDFVaccines (Basel)
November 2024
FSBSI 'Institute of Experimental Medicine', 197022 Saint Petersburg, Russia.
Background/objectives: Humoral immunity directed against neuraminidase (NA) of the influenza virus may soften the severity of infection caused by new antigenic variants of the influenza viruses. Evaluation of NA-inhibiting (NI) antibodies in combination with antibodies to hemagglutinin (HA) may enhance research on the antibody response to influenza vaccines.
Methods: The study examined 64 pairs of serum samples from patients vaccinated with seasonal inactivated trivalent influenza vaccines (IIVs) in 2018 according to the formula recommended by the World Health Organization (WHO) for the 2018-2019 flu season.
Antioxidants (Basel)
December 2024
Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre "Kurchatov Institute", 188300 Gatchina, Russia.
Viral infections and many other dangerous diseases are accompanied by the development of oxidative stress, which is a consequence of an increase in the level of the reactive oxygen species (ROS). In this regard, the search for effective antioxidants remains highly relevant. We tested fullerenol C(OH) in the context of the connection between its self-assembly in aqueous solutions and cell culture media, antiradical activity, UV cytoprotective action, and antiviral activity against international reference strains of influenza virus A(H1N1)pdm09, A(H3N2), and B subtypes in vitro on the MDCK cell line.
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