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Purpose: This study aimed to report the incidence, characteristics, and prognosis of corneal perforation in patients with leprosy.

Study Design: Retrospective observational study.

Methods: Patients who presented with leprosy and visited a specialised ophthalmology hospital (Miyata Eye Hospital, Miyazaki, Japan) between 1980 and 2020 were included.

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A systematic review of the potential treatment effects of topical epidermal growth factor for ocular surface disorders.

Cont Lens Anterior Eye

December 2024

Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Purpose: This systematic review, evaluated the role of epidermal growth factor (EGF) in corneal wound healing and the pathogenesis of ocular surface disorders (OSDs).

Methods: The clinical and experimental application of topical EGF therapy for OSDs was reviewed. This systematic research assessed articles published on PubMed/MEDLINE from 2000 to 2023 and summarized and discussed the findings of 38 experimental and 10 clinical studies.

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Article Synopsis
  • Human umbilical cord blood serum (HUCBS) shows promise as an effective treatment for severe ocular surface disorders (OSDs) by speeding up healing and reducing inflammation, benefiting patients who haven't found relief through standard therapies.
  • A study of 49 patients with various severe OSDs was conducted at San Marco Hospital in Italy, categorizing patients based on causes like rheumatologic diseases and graft-versus-host disease.
  • Results indicated significant improvement in multiple assessments, including patient-reported outcomes and clinical evaluations, demonstrating the potential of HUCBS in treating resistant cases of OSDs.
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Purpose: To review the existing literature to evaluate the utility of insulin eye drops as a treatment for neurotrophic-related epithelial defects.

Methods: A comprehensive literature search of Medline, Embase, and Web of Science and additional manual searches were conducted using relevant keywords. All articles published from January 2005 to January 2024 were examined.

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The caretaker-reversible Tarsorrhaphy.

Int Ophthalmol

October 2024

Keck School of Medicine of the University of Southern California, USC Roski Eye Institute, San Pablo Street 1450, Los Angeles, CA, 90033, USA.

Purpose: To present a modification of the reversible tarsorrhaphy that can be opened and reclosed as necessary by caretakers and the patient.

Methods: Retrospective case series of patients who underwent the reversible tarsorrhaphy. Materials included intravenous (IV) tubing as bolsters and 4-0 polypropylene suture.

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