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Evaluation of the Potential of Novel Co-Processed Excipients to Enable Direct Compression and Modified Release of Ibuprofen.

Pharmaceutics

November 2024

Department of Pharmaceutical Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.

: Improving the production rates of modern tablet presses places ever greater demands on the performance of excipients. Although co-processing has emerged as a promising solution, there is still a lack of directly compressible excipients for modified-release formulations. The aim of the present study was to address this issue by investigating the potential of novel co-processed excipients for the manufacture of modified-release tablets containing ibuprofen.

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Influence of impurities on the use of Fe-based powder as sustainable fuel.

Philos Trans A Math Phys Eng Sci

December 2024

UCLouvain, Institute of Mechanics, Materials and Civil Engineering, IMAP, Place Sainte Barbe, 2, Louvain-la-Neuve B-1348, Belgium.

Sustainable energy production, inherently transient and non-uniformly distributed around the world, requires the rapid development of sustainable energy storage technologies. Recently, pure iron powder was proposed as a high-energy density carrier. While promising, challenges are faced, such as nanoparticle emissions, micro-explosions or cavitation.

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Background: Hospital-acquired occipital pressure injuries are a preventable cause of morbidity and mortality in the perioperative setting.

Purpose: To find the occipital cushion/pillow with the lowest measured peak pressures and the highest measured surface area using pressure mapping technology.

Materials And Methods: A quality improvement project involving 3 operating room staff volunteers was conducted using pressure mapping.

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Physicochemical Methods for the Structuring and Assembly of MOF Crystals.

Acc Chem Res

August 2024

Department of Functional Materials and Catalysis, University of Vienna, Währinger Straße 42, 1090 Vienna, Austria.

ConspectusMetal-organic frameworks (MOFs) are promising for various applications through the creation of innovative materials and assemblies. This potential stems from their modular nature, as diverse metal ions and organic linkers can be combined to produce MOFs with unique chemical properties and lattice structures. Following extensive research on the design and postsynthetic chemical modification of MOF lattices at the molecular level, increasing attention is now focused on the next hierarchical level: controlling the morphology of MOF crystals and their subsequent assembly and positioning to create functional composites.

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The most significant introduction of fluidized bed combustion technology took place about 50 years ago. Initially the combustion beds were of the bubbling type. Once the designs had reached commercial application, several drawbacks were discovered: Erosion on in-bed heat-exchanger tubes, insufficient combustion and desulphurization efficiencies with coal, unfavourable scale-up to electric utility-size.

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