Local oxygen partial pressure in terms of O2-availability and pulsatile intramyocardial pressure of the left ventricular myocardium of anaesthetized open-chest dogs have been measured simultaneously by means of a piezoelectric ceramic and a platinum electrode. The tissue PO2 decreases more slowly than the pulsatile intramyocardial pressure during a transient acute occlusion of the anterior descending branch of the coronary artery. The slow decrease in the tissue PO2 seems to be explicable by the assumption that the local myocardial contractile force decreases quickly due to an unknown factor during the acute coronary occlusion and that the O2-consumption of the local myocardial tissue is reduced in accordance with the rapid decrease in the contractile force.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/978-1-4684-8890-6_57 | DOI Listing |
Turk Kardiyol Dern Ars
June 2014
Department of Cardiology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey.
A 60-year-old male with a recent anterior myocardial infarction (MI) was referred to our hospital for implantable cardioverter defibrillator (ICD) implantation. He was on the 42nd day of MI and clinically stable on admission. Electrocardiography showed right bundle branch block with QS pattern on anterior leads.
View Article and Find Full Text PDFEur J Cardiothorac Surg
February 2013
Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany.
Enormous progress has been made in paediatric heart transplantation since the first unsuccessful effort by Kantrowitz in 1967. Early reports of children undergoing heart transplantation showed alarmingly high perioperative mortality rates of 25-60%, with the diagnosis of congenital heart disease (CHD) representing a particularly high-risk subset compared with cardiomyopathy. Many of these early failures were related to poor patient selection, suboptimal immunosuppression and technical problems.
View Article and Find Full Text PDFCell Transplant
March 2008
Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany.
In end-stage heart failure, mechanical ventricular assist devices (VAD) are being used as bridge-to-transplantation, as a bridge-to-recovery, or as the definitive therapy. We tested the hypothesis that myocardial implantation of autologous bone marrow mononuclear cells (BMNC) increases the likelihood of successful weaning from left VAD (LVAD) support. Ten patients (aged 14-60 years) with deteriorating heart function underwent LVAD implantation and concomitant implantation of autologous BMNC.
View Article and Find Full Text PDFMagn Reson Med
March 2006
Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, -ational Institutes of Health, Bethesda, Maryland , USA.
In coronary circulation the flow in epicardial arteries and veins is observed to be pulsatile and out of phase with each other. Theoretical considerations predict that this phenomenon extends to all levels of the vascular tree and leads to a cyclic fluctuation of regional tissue volume. Intramyocardial tissue volume change between end-systole and end-diastole was measured noninvasively with MRI in 10 closed-chest beagles.
View Article and Find Full Text PDFJ Heart Lung Transplant
January 2004
M E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA.
Background: Although many reports demonstrate the hemodynamic benefits of left ventricular assist devices (LVAD) in right-sided circulation, it is not known whether the right ventricular myocardium goes through reverse remodeling after left ventricular mechanical circulatory support. Accordingly, the purposes of our studies were 1). to investigate the right ventricular changes that occur in fibrosis, in cellular hypertrophy, and in intra-myocardial tumor necrosis factor alpha (TNF-alpha) levels in patients receiving LVAD support; and 2).
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!