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Effects of moderate beer consumption on immunity and the gut microbiome in immunosuppressed mice.
Biosci Microbiota Food Health
August 2024
Department of Microecology, College of Basic Medical Sciences, Dalian Medical University, Dalian 116044, PR China.
Beer contains a variety of bioactive ingredients and trace elements that can regulate bodily functions, and moderate consumption of beer can enhance immune responses. This study aimed to investigate the potential benefits of moderate consumption of alcoholic or non-alcoholic beer on the gut microbiome, immunity, and intestinal barrier function in immunosuppressed BALB/c mice induced by cyclophosphamide (CTX). Model mice with CTX-induced immunosuppression were administered alcoholic or non-alcoholic beer or galacto-oligosaccharides (GOS) for 28 consecutive days.
View Article and Find Full Text PDFProtective Effects of a Sprout Hydroalcoholic Extract on Lipid Homeostasis, Hepatotoxicity, and Nephrotoxicity in Cyclophosphamide-Induced Toxicity in Rats.
Metabolites
December 2024
Department of Clinical Nutrition, Almethnab General Hospital, Qassim Health Cluster, Ministry of Health, Al Mithnab 56526, Saudi Arabia.
possesses a significant concentration of bioactive compounds and has been demonstrated to have a variety of pharmacological properties, although its sprout has not been extensively studied. Thus, the protective effects of sprout hydroalcoholic extract (BNSE) on lipid homeostasis, hepatotoxicity, and nephrotoxicity in cyclophosphamide (CYP)-induced toxicity in rats were examined in this study. Four experimental rat groups ( = 8 for each group) were examined as follows: NR, normal rats that received normal saline by oral gavage daily; CYP, injected with a single dose of CYP at 250 mg kg intraperitoneally (i.
View Article and Find Full Text PDFThe quest for bioactives that confer protection against chemotherapy induced cardio toxicity is a front-line area of cardio oncology research. Species of genus Morchella have been used in traditional medicine to treat asthma, wound healing, cough, cold, indigestion, excessive phlegm and breathlessness. M.
View Article and Find Full Text PDFSurfactin from enhances immune response and contributes to the maintenance of intestinal microbial homeostasis.
Microbiol Spectr
October 2024
MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Unlabelled: Surfactin, a lipopeptide biosurfactant produced by spp., has emerged as a promising bioactive compound due to its potent inhibitory effects on bacterial and viral pathogens. This showcases its potential as a non-antibiotic strategy for managing infectious diseases.
View Article and Find Full Text PDFPreliminary proteomic analysis of mouse lung tissue treated with cyclophosphamide and Venetin-1.
Sci Rep
October 2024
Department of Immunobiology, Institute of Biological Sciences, Curie-Skłodowska University, Lublin, Poland.
Cyclophosphamide (CPAm) is a widely used chemotherapeutic agent that exhibits potent anti-cancer properties but is often associated with debilitating side effects. Despite its efficacy, the management of CPAm-induced toxicities remains a significant clinical challenge. There has been growing interest in exploring complementary and alternative therapies to mitigate these adverse effects in recent years, and this may be a chance for the earthworm-derived preparation, Venetin-1.
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