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PLoS One
January 2025
Department of Care Ethics, University of Humanistic Studies, Utrecht, The Netherlands.
Background: People with the chronic disease Multiple Sclerosis are subjected to different degrees of profound uncertainty. Uncertainty has been linked to adverse psychological effects such as feelings of heightened vulnerability, avoidance of decision-making, fear, worry, anxiety disorders, and even depression. Research into Multiple Sclerosis has a predominant focus on the scientific, practical, and psychosocial issues of uncertainty.
View Article and Find Full Text PDFLife Sci Space Res (Amst)
February 2025
Institute of Environmental Systems Biology, College of Environmental Science and Engineering, Dalian Maritime University, Dalian, 116026, Liaoning, PR China.
The space environment presents unique stressors, such as microgravity and space radiation, which can induce molecular and physiological changes in living organisms. To identify key reproducible transcriptomic features and explore potential biological roles in space-flown C. elegans, we integrated transcriptomic data from C.
View Article and Find Full Text PDFUltrason Sonochem
January 2025
School of Traditional Chinese Medicine and Food Engineering, Shanxi Provincial Key Laboratory of Traditional Chinese Medicine Processing, Shanxi University of Chinese Medicine, Jinzhong 030619, PR China. Electronic address:
Polysaccharides from the dried tuber of Typhonium giganteum Engl. (TGEPs) were obtained by utilizing ultrasonic-assisted extraction (UAE) as the extraction method. The determination of optimal process parameters for the UAE of TGEPs (TGEP-U) was accomplished through the application of response surface methodology (RSM).
View Article and Find Full Text PDFSci Total Environ
January 2025
Civil Engineering Department, Indian Institute of Technology, Palakkad, Kerala, India.
This study investigates the spatio-temporal consistency of different MMDI formulations and their role in meteorological drought characterization uncertainty under historic and future climates using ERA5 reanalysis, and outputs from eight Coupled Model Intercomparison Project Phase 6 models, respectively, across different climate zones and shared socioeconomic pathways (SSP) in the Indian subcontinent. Six MMDI formulations namely the Standardized Precipitation Evaporation Index (SPEI), Reconnaissance Drought Index (RDI), and self-calibrated Palmer Drought Severity Index (scPDSI), Standardized Palmer Drought Index (SPDI), Standardized Moisture Anomaly Index (SZI) and Supply Demand Drought Index (SDDI) are used. A suite of analysis including agreement mapping, category difference analysis and uncertainty contribution analysis using global sensitivity analysis (GSA) are employed to quantify the consistency of MMDIs and uncertainty in drought characterization due to the MMDI formulation.
View Article and Find Full Text PDFJ Environ Manage
January 2025
Hugh Downs School of Human Communication, United States.
This paper reports a theoretically-driven quantitative content analysis of news media discourse on climate change, its effects, and solutions to understand how US news discourse differs from widely supported scientific conclusions on global climate. Despite the dire warnings and calls to action, US public opinion on the causes and solutions to climate change remain divided. In the global context, the US's split views are anomalous and may be an artifact of the US media's coverage of the climate crisis.
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