Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Neurodevelopmental Abnormalities in Down Syndrome: Assessing Structural and Functional Deficits.
Cureus
December 2024
Department of Physiology, Touro College of Osteopathic Medicine, Middletown, USA.
Down syndrome (DS) is a genetic intellectual disorder caused by trisomy of chromosome 21 (Hsa21) and presents with a variety of phenotypes. The correlation between the chromosomal abnormality and the resulting symptoms is unclear, partly due to the spectrum of impairments observed. However, it has been determined that trisomy 21 contributes to neurodegeneration and impaired neurodevelopment resulting from decreased neurotransmission, neurogenesis, and synaptic plasticity.
View Article and Find Full Text PDFThe transcriptional regulation effects of histidine, isoleucine and glutamate on free exopolysaccharide biosynthesis of 937.
Front Microbiol
January 2025
Key Lab of Dairy Biotechnology and Safety Control, Yangzhou University, Yangzhou, Jiangsu, China.
Introduction: The free exopolysaccharide (f-EPS) produced by is a natural texture modifier and has a variety of prebiotic activities. Our previous studies showed f-EPS production from 937 was increased 2-fold in the presence of 15 mM of glutamate, isoleucine, and histidine in the chemically defined medium.
Methods: In this study, we used transcriptomics and qPCR to further explore the specific mechanism of the enhanced effect of 3 amino acids on the f-EPS biosynthesis of 937.
Revealing differences in flavor compounds during plum wine fermentation using single and mixed yeast strains through metabolomic analysis.
Food Chem X
January 2025
Institute of Agro-Products Processing Science and Technology / Institute of Food Nutrition and Health, Sichuan Academy of Agricultural Sciences, No. 60 Shizishan Road, Jinjiang District, Chengdu City, Sichuan 610000, China.
Mixed fermentation can enhance the flavor and aroma of fruit wine, but the mechanisms driving this enhancement remain unclear. This study used non-targeted metabolomics to analyze the effects of mixed versus single fermentation on plum wine flavor. The results showed that compared with single fermentation, mixed fermentation reduced ethanol content and the ability to consume reducing sugars.
View Article and Find Full Text PDFAnalysis of differential metabolites in Liuyang douchi at different fermentation stages based on untargeted metabolomics approach.
Food Chem X
January 2025
College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.
The quality and flavor of Liuyang Douchi are usually closely related to the metabolites compostion. This work described the metabolic profiles of Liuyang douchi during fermentation. Obvious hydrolysis of carbohydrates, proteins and slight lipids degradation were observed.
View Article and Find Full Text PDFTracing of Amino Acids Dynamics in Cell Lines Based on O Stable Isotope Labeling.
Anal Chem
January 2025
Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Ankara 06230, Turkey.
Metabolite levels and turnover rates are necessary to understand metabolomic dynamics in a living organism fully. Amino acids can play distinct roles in various cellular processes, and their abnormal levels are associated with pathological conditions, including cancer. Therefore, their levels, especially turnover rates, may provide enormous information about a phenotype.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!