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Investigation of the preliminary mechanism of action for the acute anti-inflammatory activity of the methanol extract of Smilax ornata Lem.
J Ethnopharmacol
February 2020
Section of Pharmacology and Pharmacy, Department of Basic Medical Sciences, University of the West Indies, Mona, Kingston 7, Jamaica. Electronic address:
Ethnopharmacological Relevance: In folkloric medicine the dried rhizome of the Jamaican sarsaparilla (Smilax ornate Lem.), is given as a decoction to treat chronic rheumatism and rheumatoid arthritis. This particular claim has been scientifically validated; however, the mechanism for its anti-inflammatory activity is still unknown and hence, it forms the reason for this investigation.
View Article and Find Full Text PDFCervical ripening with low-dose prostaglandins in planned vaginal birth after cesarean.
PLoS One
June 2014
Service de Gynécologie Obstétrique, Hôpital Robert Debré, AP-HP, Paris, France ; Université Paris Diderot, Paris, France.
Objectives: To compare uterine rupture, maternal and perinatal morbidity rates in women with one single previous cesarean after spontaneous onset of labor or low-dose prostaglandin-induced cervical ripening for unfavourable cervix.
Study Design: This was a retrospective cohort study of 4,137 women with one single previous cesarean over a 22-year period. Inpatient prostaglandin administration consisted in single daily local applications.
Rupture of the scarred uterus.
Acta Obstet Gynecol Scand
July 2007
Department of Gynecology and Obstetrics, University Hospital of Caen, France.
Objective: To assess the risk of uterine rupture of the scarred uterus according to mode of delivery in subsequent births recorded as spontaneous labour, labour induced by oxytocin, labour after ripening with prostaglandin E2, and planned cesarean section.
Methods: Retrospective study of 2,128 births with a low transversal scar after a previous cesarean section. The study population was realised in a level III university hospital from 1995 to 2003.
Peripheral neuronal nitric oxide synthase activity mediates the antinociceptive effect of Crotalus durissus terrificus snake venom, a delta- and kappa-opioid receptor agonist.
Life Sci
June 2004
Laboratório de Fisiopatologia, Instituto Butantan, Avenida Vital Brazil, 1500, 05503-900, São Paulo, SP, Brazil.
Previous work has shown that nitric oxide (NO) mediates the antinociceptive effect of Crotalus durissus terrificus venom on carrageenin-induced hyperalgesia. In the present study the role of constitutive neuronal or of inducible form of nitric oxide synthase on venom effect was determined. The rat paw prostaglandin E(2) (PGE(2))-induced mechanical hyperalgesia model was used for nociceptive evaluation.
View Article and Find Full Text PDFCommittee opinion. Induction of labor for vaginal birth after cesarean delivery.
Obstet Gynecol
April 2002
A recent population-based study of vaginal birth after cesarean delivery (VBAC) attempts observed uterine rupture rates of 24.5 per 1,000 with prostaglandin-induced labor, while the uterine rupture rates with spontaneous labor and labor induced without prostaglandins were lower (5.2/1,000 and 7.
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