Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Fluorescence detection of protamine, heparin and heparinase II based on a novel AIE molecule with four carboxyl.
Int J Biol Macromol
August 2020
Chongqing Key Laboratory of Green Synthesis and Applications, College of Chemistry, Chongqing Normal University, Chongqing, China. Electronic address:
In this research, a new DSA (Distyryl-anthracene) derivative with four carboxyl groups was designed and synthesized. This molecule exhibits aggregation-induced emission property (AIE). With the AIE character, a convenient and sensitive fluorescent probe for the detection of protamine, heparin and heparinase has been developed.
View Article and Find Full Text PDFHeterogeneity in neutrophil responses to immune complexes.
Blood Adv
October 2019
Division of Hematology and.
Immune complexes (ICs) can trigger inflammation and thrombosis, in part, by activating neutrophils. Much attention has focused on the serologic characteristics of ICs and Fc receptors associated with cellular activation, but few studies have examined host susceptibility to neutrophil activation by ICs. Here, we use a novel whole blood system to investigate the ability of ICs to cause neutrophil activation and degranulation.
View Article and Find Full Text PDFActivated platelet aggregation is transiently impaired also by a reduced dose of protamine.
Scand Cardiovasc J
December 2019
Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.
Protamine reduces platelet aggregation after cardiopulmonary bypass (CPB). We studied the inhibitory effect of a reduced protamine dose, the duration of impaired platelet function and the possible correlation to postoperative bleeding. Platelet function was assessed by impedance aggregometry in 30 patients undergoing cardiac surgery with CPB at baseline, before protamine administration, after 70% and 100% of the calculated protamine dose, after 20 minutes and at arrival to the intensive care unit.
View Article and Find Full Text PDFArgatroban in Thrombocytopenic Patients Sensitized to Circulating Protamine-Heparin Complexes.
J Cardiothorac Vasc Anesth
October 2017
Department of Anesthesia, Critical Care and Pain Medicine, Division of Cardiothoracic and Vascular Anaesthesia and Intensive Care, Medical University of Vienna, Vienna, Austria. Electronic address:
Clinically applicable magnetic-labeling of natural killer cells for MRI of transcatheter delivery to liver tumors: preclinical validation for clinical translation.
Nanomedicine (Lond)
April 2016
Departments of Radiology, Northwestern University, 737 N Michigan Ave, Suite 1600, Chicago, IL 60611, USA.
Aim: To test the hypothesis that MRI can monitor intraportal vein (IPV) transcatheter delivery of clinically applicable heparin-protamine-ferumoxytol (HPF) nanocomplex-labeled natural killer (NK) cells to liver tumor.
Materials & Methods: Liver tumor rat models underwent catheterization for IPV infusion of HPF-labeled NK cells (NK-92MI cell line). MRI measurements within tumor and adjacent liver tissues were compared pre- and post-NK cell infusion.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!