The repeated exposure to cold of 2-month- and 2-year-old rats resulted in an important depression of the activity of numerous enzymes in the adrenal cortex. The simultaneous treatment with Aslavital administered in successive doses prevented the decrease of the enzymic activity. It seems that Aslavital exerted a stimulating action on the biosynthesis processes of glucocorticoid hormones and subsequently induced the processes of acclimatization to cold in rats submitted to treatment.

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