The respiratory symptoms of gastro-oesophageal reflux, which sometimes includes massive and fatal inhalation, are well-known in infants. In older children the digestive signs are not clinically evident and the reflux mainly, if not exclusively, can be translated by recurring respiratory symptoms. The series of 36 cases presented in this work concerns children between 3 months and 15 years old, for whom the first signs were respiratory, with often a silent gastro-oesophageal reflux for several months, and even several years in some cases. The physiopathology of the respiratory symptoms concerns principally the repeated alimentary aspiration and/or gastric content during nocturnal decubitus. The pulmonary lesions caused by the reflux can be either localized, with atelectasis, obstructive emphysema or bronchiectasis, or generalized with granulomatous reactions around the food particles. Other respiratory conditions such as asthma or cystic fibrosis can be also associated with gastro-oesophageal reflux. The diagnostic criteria are discussed.
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J Bras Pneumol
January 2025
. Laboratório de Função Pulmonar, Instituto de Assistência ao Servidor Público Estadual de São Paulo Francisco Morato Pereira - IAMSPE-FMO - São Paulo (SP), Brasil.
The latest pulmonary function guideline from the Brazilian Thoracic Association was published in 2002, since which there have been updates to international guidelines (mainly those from the European Respiratory Society and the American Thoracic Society), as well as new national and international publications on various aspects of the performance, interpretation, and clinical implications of spirometry. Despite those updates, a careful analysis of what applies to the reality in Brazil is essential, because there have been studies that evaluated individuals who are representative of our population and who could show responses different from those of individuals in other regions of the world. This document is the result of the work of a group of specialists in pulmonary function who evaluated relevant scientific articles that could be applicable to the population of Brazil.
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School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
The aim of this study was to determine whether the effects of extreme but discrete PM2.5 exposure from a coal mine fire on respiratory symptoms abated, persisted, or worsened over time, and whether they were exacerbated by COVID-19. We analysed longitudinal survey data from a cohort residing near a 2014 coalmine fire in regional Australia.
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Sydney Medical School, University of Sydney, Sydney, New South Wales (NSW), Australia.
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View Article and Find Full Text PDFJMIR Res Protoc
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Clinical Informatics and Health Outcomes Research Group, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
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