In previous paper, the role of somatostatin in diabetes was examined. Here, the inhibitive action of somatostatin on growth hormone and its physiopathological and therapeutic implications in acromegaly and diabetes mellitus are reanalysed. The effect of the polypeptide on the C.N.S. is looked at from the viewpoint of its role as neurotransmitter at encephalic level and of its therapeutic use.
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