Investigations were carried out on the immunogenesis and the serum-protein profile in the treatment of broilers with the protein hydrolysate Hydroprot as well as with Newcastle disease vaccine. The treatment with Hydroprot led to a lower average geometric titer of antibodies--6.4 on the 14th, 6.9 on the 24th, and 6.6 on the 39th day following immunization. Characteristic changes in the serum-protein profile were established--decrease in the total serum-protein, increase in the globulins and particularly in the fractions the peak level of which corresponded to the period of most strongly expressed immunity. The results obtained were associated with the involvement of amino acid synthesis in the immunologic process. They showed that under the effect of the preparation applied there set in enhanced immunogenesis as an expression of changed immune responsiveness.

Download full-text PDF

Source

Publication Analysis

Top Keywords

serum-protein profile
8
[effect preparation
4
preparation hydroprot
4
hydroprot immunogenesis
4
immunogenesis birds
4
birds newcastle
4
newcastle disease]
4
disease] investigations
4
investigations carried
4
carried immunogenesis
4

Similar Publications

Rapid reduction of body size in populations responding to global warming suggests the involvement of temperature-dependent physiological adjustments during growth, such as mitochondrial alterations, in the efficiency of producing metabolic energy, a process that is poorly explored, especially in endotherms. Here, we examined the mitochondrial metabolism and proteomic profile of red blood cells in relation to body size and cellular energetics in nestling shearwaters (Calonectris diomedea) developing at different natural temperatures. We found that nestlings of warmer nests had lighter bodies and smaller beaks at fledging.

View Article and Find Full Text PDF

Implication of fibroblast growth factor 7 in ovarian cancer metastases and patient survival.

Front Oncol

January 2025

Gynecologic Oncology Section, Stephenson Cancer Center, Obstetrics and Gynecology Department, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.

Background/objectives: Patients with ovarian cancer commonly experience metastases and recurrences, which contribute to high mortality. Our objective was to better understand ovarian cancer metastasis and identify candidate biomarkers and drug targets for predicting and preventing ovarian cancer recurrence.

Methods: Transcripts of 770 cancer-associated genes were compared in cells collected from ascitic fluid versus resected tumors of an ES-2 orthotopic ovarian cancer mouse model.

View Article and Find Full Text PDF

Impact of trypanosomiasis on male camel infertility.

Front Vet Sci

January 2025

Zoology and Entomology Department, Faculty of Science, New Valley University, El-Kharga, Egypt.

Introduction: Blood parasitism is a significant clinical disease that silently undermines the livestock industry, particularly affecting camels. This study aimed to assess the prevalence of in Arabian camels () and its impact on infertility by examining serum protein fractions, lipids, reproductive indices, and the expression of heat shock protein (HSP70) during breeding season.

Methods: A total of 107 male post-pubertal camels, aged between 5 and 10 years, were collected randomly from slaughtering house in Assiut Governorate, Egypt.

View Article and Find Full Text PDF

The prevalence of Alzheimer's disease (AD) is increasing as society ages. The details of AD pathogenesis have not been fully elucidated, and a comprehensive gene expression analysis of the process leading up to the onset of AD would be helpful for understanding the mechanism. We performed an RNA sequencing analysis on a cohort of 1227 Japanese blood samples, representing 424 AD patients, 543 individuals with mild cognitive impairment (MCI), and 260 cognitively normal (CN) individuals.

View Article and Find Full Text PDF

Remimazolam (Byfavo, Acacia Pharma), a recent Food and Drug Administration-approved ester-linked benzodiazepine, offers advantages in sedation, such as rapid onset and predictable duration, making it suitable for broad anesthesia applications. Its favorable pharmacological profile is primarily attributed to rapid hydrolysis, the primary metabolism pathway for its deactivation. Thus, understanding remimazolam hydrolysis determinants is essential for optimizing its clinical use.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!