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René Couteaux (1909-1999) and the morphological identification of synapses.
Biol Cell
August 2006
Département de Cytologie, Université Pierre et Marie Curie, 7 Quai Saint Bernard, 75005 Paris, France.
During a historical research, we realized that René Couteaux (1909-1999) was the first histologist who stained the postsynaptic structure of the neuromuscular junction. By means of Janus Green B dye, he revealed the membranous 'subneural apparatus' related to the 'synaptic gutter'. Hence, he justified the use of the physiological term 'synapse' in histology.
View Article and Find Full Text PDFStress-induced injury of pig myocardium is accompanied by increased lipid peroxidation and depletion of mitochondrial ATP.
Exp Pathol
April 1992
Postgraduate Medical School, Polish Academy of Sciences, Warsaw.
The aim of the study was to investigate the mechanisms of myocardial lesions induced by stress in conscious, intact pigs. The animals were subjected to 24 h immobilization, controls were kept in normal conditions. The pigs were killed by electric shock and exsanguination.
View Article and Find Full Text PDFEffect of nisoldipine on stress-induced myocardial damage in the conscious pig.
Clin Exp Pharmacol Physiol
January 1990
Medical Research Centre, Polish Academy of Sciences, Warsaw.
1. The effect of the calcium channel blocker nisoldipine on the myocardial content of lipid peroxidation products (malondialdehyde (MDA), conjugated double bonds (CDB), fluorescent end-products (RF) and mitochondrial adenine nucleotides) was investigated in conscious pigs (n = 14) subjected to 24 h of immobilization stress. Histoenzymatic and electron microscopic studies of the myocardium were also performed.
View Article and Find Full Text PDF[Tests of contracture and sensitivity to malignant hyperthermia in 27 patients].
Ann Fr Anesth Reanim
June 1988
Département d'Anesthésie-Réanimation Chirurgicale, Hôpital B, CHR, Lille.
Twenty-seven patients, four of whom had presented with a crisis of malignant hyperthermia and the 23 other being close relatives of such patients, underwent a muscle biopsy so as to determine their susceptibility to malignant hyperthermia. Halothane-caffeine contracture tests, interpreted in accordance with the criteria of the European Group on Malignant Hyperthermia, yielded the following results: 13 positive (MHS), 10 negative (MHN), 4 equivocal (MHE). The history, clinical examination, CPK level, histoenzymatic morphology and electron microscopic study did not provide information sensitive enough to use for the detection of susceptibility to malignant hyperthermia.
View Article and Find Full Text PDFThe metabolic apport of prokaryotic symbionts in the fat body of Blattella germanica was investigated by histoenzymatic methods, using chlortetracycline-treated and normal strains. In the experimental insects, bacteriocytes showed a decreased oxidoreductase activity, whereas the staining intensity of the other cell types was generally unchanged. Electron microscopic observations showed that some bacteria were still present in the bacteriocytes of the treated insects, but exhibited degeneration patterns to a different extent; therefore, they are not likely to carry on any enzymatic activity.
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