Idiopathic juvenile retinoschisis is a sex-linked disease, which generally involves the macula and the retinal periphery in 50% of cases. The authors report a case of juvenile retinoschisis in which the central schisis was associated with wide non-perfused retinal areas causing the growth of retinal and epipapillary neovascularizations in one eye. The new vessels produced an intravitreal hemorrhage. The arising of non-perfused retinal areas is probably determined by capillary insufficiency secondary to the alteration of its vascular trophism due to the retinal detachment. This may cause a break of the blood-retinal barrier with subsequent capillary occlusions. We performed laser photocoagulation of the non-perfused areas, and complete regression of the neovascularization was obtained.

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