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Benchmarking the clinical outcomes of Healthentia SaMD in chronic disease management: a systematic literature review comparison.
Front Public Health
December 2024
AstraZeneca SpA, Milano Innovation District (MIND), Milano, Italy.
Background: Software as a Medical Device (SaMD) and mobile health (mHealth) applications have revolutionized the healthcare landscape in the areas of remote patient monitoring (RPM) and digital therapeutics (DTx). These technological advancements offer a range of benefits, from improved patient engagement and real-time monitoring, to evidence-based personalized treatment plans, risk prediction, and enhanced clinical outcomes.
Objective: The systematic literature review aims to provide a comprehensive overview of the status of SaMD and mHealth apps, highlight the promising results, and discuss what is the potential of these technologies for improving health outcomes.
Unveiling multiscale spatiotemporal dynamics of volatility in high-frequency financial markets.
PLoS One
December 2024
Department of Finance, Zhejiang University of Finance and Economics, Hangzhou, China.
This study explores the intricate dynamics of volatility within high-frequency financial markets, focusing on 225 of Chinese listed companies from 2016 to 2023. Utilizing 5-minute high-frequency data, we analyze the realized volatility of individual stocks across six distinct time scales: 5-minute, 10-minute, 30-minute, 1-hour, 2-hour, and 4-hour intervals. Our investigation reveals a consistent power law decay in the auto-correlation function of realized volatility across all time scales.
View Article and Find Full Text PDFDesigning of immunodiagnostic assay using polyclonal antibodies for detection of Enteropathogenic Escherichia coli strains.
PLoS One
January 2025
Institute of Biotechnology, Addis Ababa University, Addis Ababa, Ethiopia.
Enteropathogenic Escherichia coli (EPEC) is a significant bacterial pathogen that causes infantile diarrhea, particularly in low- and middle-income countries. The lack of a reliable diagnostic method greatly contributes to the increased occurrence and severity of the disease. This study aimed at developing of a cost-effective, rapid, and efficient immunodiagnostic assay for detecting EPEC infection.
View Article and Find Full Text PDFEffectiveness of Virtual Reality Training in Improving Outcomes for Dialysis Patients: Systematic Review and Meta-Analysis.
J Med Internet Res
January 2025
Department of Center for Hemodialysis, The Second Hospital of Dalian Medical University, Dalian, China.
Background: Virtual reality (VR) training uses computer-generated simulations that enable users to engage with immersive virtual environments, simulating real-world activities or therapeutic exercises. This technology is increasingly recognized as a promising intervention to address the physical and psychological challenges faced by dialysis patients, who frequently experience diminished physical function, social isolation, and emotional distress associated with prolonged treatment regimens. Given the increasing prevalence of dialysis patients and the limitations of conventional rehabilitation approaches, VR presents a novel, interactive method that has the potential to enhance patient well-being and improve quality of life.
View Article and Find Full Text PDFFrom dusk to dawn: examining how adolescents engage with digital media using objective measures of screen time in a repeated measures study.
Int J Behav Nutr Phys Act
January 2025
Department of Medicine, University of Otago, PO Box 56, Dunedin, 9010, New Zealand.
Background: Although evening screen time is thought to impair subsequent sleep, current measures are limited to questionnaires which seem unlikely to accurately assess screen time in youth. Given the ubiquitous nature of digital devices, improving measurement of screen time is required before related health effects can be appropriately determined. The aim of this study was to objectively quantify screen time before sleep using video camera footage.
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