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Causes of hospitalization and mortality in persons with epilepsy: The EpiLink Bologna cohort, Italy.
Eur J Neurol
February 2025
Full Member of the European Reference Network for Rare and Complex Epilepsies (EpiCARE), IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Background: Epilepsy significantly impacts on morbidity and mortality. Understanding hospitalization and mortality risks in persons with epilepsy (PWE) is essential for improving healthcare strategies. We aimed to investigate the risk and causes of hospitalization and mortality in PWE compared to a matched general population cohort.
View Article and Find Full Text PDFMVP-VSASL: measuring MicroVascular Pulsatility using velocity-selective arterial spin labeling.
Magn Reson Med
April 2025
Center for Functional MRI, University of California San Diego, La Jolla, California, USA.
Purpose: By leveraging the small-vessel specificity of velocity-selective arterial spin labeling (VSASL), we present a novel technique for measuring cerebral MicroVascular Pulsatility named MVP-VSASL.
Theory And Methods: We present a theoretical model relating the pulsatile, cerebral blood flow-driven VSASL signal to the microvascular pulsatility index ( ), a widely used metric for quantifying cardiac-dependent fluctuations. The model describes the dependence of the of VSASL signal (denoted ) on bolus duration (an adjustable VSASL sequence parameter) and provides guidance for selecting a value of that maximizes the SNR of the measurement.
Background: Sarcopenia, characterized by declining muscle mass and function, is a growing concern among India's aging population. This study investigates sarcopenia's prevalence and determinants using the nationally representative LASI dataset.
Methods: This analysis included 26,780 community-dwelling adults aged 60 and above, with informed consent obtained from all participants.
Oxygen Consumption and Metabolic Equivalents During Physical Activities in Stroke: A Systematic Review.
Physiother Res Int
April 2025
Department of Rehabilitation and Care, Hatsudai Rehabilitation Hospital, Tokyo, Japan.
Background And Purpose: Patient education on physical activity (PA) requires a clear understanding of PA intensity. However, there is no organized list of PAs intensities specific to individuals with stroke. This review aimed to clarify the intensity of PAs in people with stroke and summarize the methodologies and participant characteristics in previous investigations of energy expenditure (EE) during PAs.
View Article and Find Full Text PDFPlasma proteomic characterization of motoric cognitive risk and mild cognitive impairment.
Alzheimers Dement
January 2025
Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, Maryland, USA.
Introduction: Motoric cognitive risk (MCR) is a pre-dementia syndrome characterized by mobility and cognitive dysfunction. This study conducted a proteome-wide study of MCR and compared the proteomic signatures of MCR to that of mild cognitive impairment (MCI).
Methods: Participants were classified as MCR using a memory questionnaire and 4-meter walk.
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