Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0021-9673(00)84199-0 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
High performance liquid chromatography (HPLC) is a key analytical technique that is used in a number of fields. Improving the separation efficiency, stability, and universality of HPLC has been a continuing analytical-chemistry focus. In chromatographic separation, factors such as the composition and ratio of the mobile phase, the type of stationary phase, and the dimensions of the chromatographic column significantly affect the separation efficiency.
View Article and Find Full Text PDFMechanisms of the Compound of Magnoliae Flos and Xanthii Fructus Essential Oils for the Treatment of Allergic Rhinitis based on the Integration of Network Pharmacology, Molecular Docking, and Animal Experiment.
Comb Chem High Throughput Screen
January 2025
Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Aim And Objective: Magnoliae Flos (Chinese name: Xin-Yi) and Xanthii Fructus (Chinese name: Cang-Er-Zi) are Chinese herbal medicines and have been used to treat allergic rhinitis (AR). However, the therapeutic effect, active ingredients, and probable processes of a compound of Magnoliae Flos and Xanthii Fructus in the form of essential oils (CMFXFEO) in treating AR have not been reported. This study aims to determine the efficacy of the CMFXFEO on ovalbumin (OVA)-induced AR in a rat model and to use network pharmacology and molecular docking to reveal the hub genes, biological functions, and signaling pathways of CMFXFEO against AR.
View Article and Find Full Text PDFBroad-spectrum affinity chromatography of SARS-CoV-2 and Omicron vaccines from ligand screening to purification.
J Chromatogr A
January 2025
Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300350, China; Key Laboratory of Systems Bioengineering and Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin University, Tianjin 300350, China. Electronic address:
Emerging variants of SARS-CoV-2 pose great technological and regulatory challenges to vaccine manufacturing, especially in downstream processing. To address this dilemma, the development of broad-spectrum affinity chromatography for the purification of wild-type SARS-CoV-2 and its variants is crucial. We propose a comprehensive strategy to achieve this goal via the identification of high-affinity peptides by affinity selection of phage display and next-generation sequencing (NGS) and the evaluation of chromatographic performance.
View Article and Find Full Text PDFAssessment of thiamine and riboflavin levels in common green leafy vegetables grown in Shariatpur, Bangladesh.
Heliyon
January 2025
Department of Chemistry, University of Dhaka, Dhaka-1000, Bangladesh.
Thiamine (vitamin B1) and riboflavin (vitamin B2) are essential vitamins because of their important health impact. Twelve different green leafy vegetable-samples including , and indigenous to Shariatpur district in Bangladesh were collected, dried, stored and analyzed. The extraction procedures involved acid hydrolysis followed by enzymatic hydrolysis of the dried vegetable samples.
View Article and Find Full Text PDFGlobal retention model based on multisample system parameters for optimising chromatographic fingerprints of medicinal plants.
Anal Chim Acta
February 2025
Department of Analytical Chemistry, Faculty of Chemistry, Universitat de València, C/ Dr. Moliner 50, 46100, Burjassot, Spain. Electronic address:
Background: Developing analytical methods for Traditional Medicine products by liquid chromatography is challenging due to their chemical complexity and the lack of analytical standards for numerous, unidentified constituents. Regulatory agencies recommend chromatographic fingerprint analysis for quality evaluation, relying on peak detection to ensure resolution. Conventional modelling struggles to optimise experimental conditions for such complex samples.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!