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Introduction: Major Depressive Disorder (MDD) leads to dysfunction and impairment in neurological structures and cognitive functions. Despite extensive research, the pathophysiological mechanisms and effects of MDD on the brain remain unclear. This study aims to assess the impact of MDD on brain activity using EEG power spectral analysis and asymmetry metrics.

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Extended performance of cognitively demanding tasks induces cognitive fatigue manifested with an overall deterioration of behavioral performance. In particular, long practice with tasks requiring impulse control is typically followed by a decrease in self-control efficiency, leading to performance instability. Here, we show that this is due to changes in activation modalities of key task-related areas occurring if these areas previously underwent intensive use.

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Beyond Averaging: A Transformer Approach to Decoding Event Related Brain Potentials.

Neuroimage

January 2025

Department of Computer Science, University of Innsbruck, Technikerstrasse 21a, Innsbruck, 6020, Austria. Electronic address:

The objective of this study is to assess the potential of a transformer-based deep learning approach applied to event-related brain potentials (ERPs) derived from electroencephalographic (EEG) data. Traditional methods involve averaging the EEG signal of multiple trials to extract valuable neural signals from the high noise content of EEG data. However, this averaging technique may conceal relevant information.

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Background: Anesthesia depth influences seizure quality in patients undergoing electroconvulsive therapy (ECT). EEG-based neuromonitoring has been shown to detect adequate anesthesia depth for ECT. Anesthesia depth-guided ECT management may therefore be a reliable alternative to the predetermined anesthesia-to-stimulation time interval.

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Brain changes in sleep-related hypermotor epilepsy observed from wakefulness and N2 sleep: A matched case-control study.

Clin Neurophysiol

January 2025

Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China. Electronic address:

Objective: Sleep-related hypermotor epilepsy (SHE) is a relatively uncommon epilepsy syndrome, characterized by seizures closely related to the sleep cycle. This study aims to explore interictal electroencephalographic (EEG) characteristics in SHE.

Methods: We compared EEG data from 20 patients with SHE, 20 patients with focal epilepsy (FE), and 14 healthy controls, carefully matched for age, sex, education level, epilepsy duration, and drug-resistant epilepsy.

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