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Unravelling the fatal chain: A detailed investigation into catastrophic events following anaesthesia in a feline patient.
Vet Anaesth Analg
February 2025
Langford Vets, University of Bristol, Langford, UK.
An 8-year-old male neutered British Shorthair cat, weighing 5.12 kg, was referred for chronic mild inappetence, lethargy, bilirubinuria, weight loss and icterus. Diagnostic imaging and serum biochemistry suggested a partial biliary tract obstruction caused by an enlarged pancreas.
View Article and Find Full Text PDFPirfenidone to prevent fibrosis in acute respiratory distress syndrome: The PIONEER study protocol.
Contemp Clin Trials
March 2025
Department of Anesthesia and Critical Care, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Background: Pulmonary fibrosis is a major complication of the Acute Respiratory Distress Syndrome (ARDS). Pirfenidone is an approved treatment for idiopathic pulmonary fibrosis. It may attenuate ARDS-related fibrosis and decrease the need for prolonged ventilation.
View Article and Find Full Text PDFComparison of remimazolam tosylate and propofol in hemodynamic stability, postoperative cognitive function, and recovery in general anesthesia combined with regional nerve blocks: a retrospective cohort study.
BMC Anesthesiol
March 2025
Anesthesia and Surgery Center, Ziyang Central Hospital, No. 66, Rende West Road, Yanjiang District, Ziyang City, Sichuan Province, 641300, China.
Background: General anesthesia (GA) combined with regional anesthesia (RA) is commonly used to enhance perioperative analgesia and hemodynamic stability. This study aimed to compare the hemodynamic effects and postoperative cognitive function between remimazolam tosylate and propofol in patients undergoing GA combined with RA.
Methods: A retrospective cohort study was conducted on 4408 patients who underwent elective upper or lower limb surgeries at our institution from January 2020 to June 2024.
Clinical predictors of extubation failure in postoperative critically ill patients: a post-hoc analysis of a multicenter prospective observational study.
BMC Anesthesiol
March 2025
Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, 2-15 Yamadaoka, Suita, 565-0871, Osaka, Japan.
Background: Postoperative patients constitute majority of critically ill patients, although factors predicting extubation failure in this group of patients remain unidentified. Aiming to propose clinical predictors of reintubation in postoperative patients, we conducted a post-hoc analysis of a multicenter prospective observational study.
Methods: This study included postoperative critically ill patients who underwent mechanical ventilation for > 24 h and were extubated after a successful 30-min spontaneous breathing trial.
Etomidate and its derivatives: time to say goodbye? Br J Anaesth 2024; 134: 11-13.
Br J Anaesth
March 2025
Department of Anesthesiology, Duke University, Durham, NC, USA; Bermaride LLC, Durham, NC, USA.
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