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Drug-induced renal tubular acidosis in a patient receiving trimethoprim-sulfamethoxazole.
BMJ Case Rep
January 2025
General Surgery, Changi General Hospital, Singapore.
An Asian woman in her 70s was started on trimethoprim-sulfamethoxazole (TMP-SMX) for treatment of her left fourth toe osteomyelitis. During the course of her therapy, she developed renal tubular acidosis despite being immunocompetent with no known renal disease. Cessation of TMP-SMX and supportive care resulted in resolution of her condition.
View Article and Find Full Text PDFRespiratory and hematological physiology of day 15 chicken embryos (Gallus gallus domesticus) during water submergence and air recovery: Implications for bird embryos experiencing nest inundation.
Comp Biochem Physiol A Mol Integr Physiol
January 2025
Developmental Integrative Biology, Department of Biological Sciences, University of North Texas, 1155 Union Circle #305220, Denton, TX 76203, United States of America.
Bird nests of coastal or inland breeding birds can temporarily flood during high tides or storms. However, respiratory physiological disruption of such water submersion and implications for post-submergence survival are poorly understood. We hypothesized that respiratory physiological disturbances caused by submersion would be rapidly corrected following return to normal gas exchange across the eggshell, thus explaining survival of nest inundation in the field.
View Article and Find Full Text PDFLife-threatening dapagliflozin-associated euglycaemic diabetic ketoacidosis in a postoperative patient.
BMJ Case Rep
January 2025
Kasturba Medical College Mangalore, Mangalore, Karnataka, India
Euglyceamic diabetic ketoacidosis (EuDKA) is an uncommon but serious diabetes mellitus complication associated with risk factors such as fasting, surgery, pregnancy and, more recently, the use of sodium-glucose cotransporter-2 inhibitors (SGLT2i). This case is of a woman with type 2 diabetes and hypertension in her 50s who underwent an incarcerated umbilical hernia repair and abdominoplasty. Two days after discharge, she was readmitted with nausea, vomiting, loss of appetite, low-grade fever and breathing difficulty.
View Article and Find Full Text PDFEvaluation and Improving the Quality of Arterial Blood Gas Interpretation Among Junior Doctors in Aswan University Hospital: A Clinical Audit.
Cureus
December 2024
Pulmonary Medicine, Aswan University Hospitals, Aswan, EGY.
Article Synopsis
- Arterial blood gas (ABG) analysis is crucial for diagnosing critical conditions in patients, and misinterpretation can lead to serious management issues.
- A study conducted at Aswan University Hospitals involved 273 healthcare professionals and assessed their ABG interpretation skills before and after targeted educational interventions over two weeks.
- Results indicated significant improvements, with accuracy in interpreting ABG results increasing from 71.8% to 90.2% and enhanced skills in identifying acid-base disturbances and distinguishing between respiratory and metabolic issues.
Intraoperative ST Segment Depression During General Anesthesia in a Child: Early Detection of Hypertrophic Cardiomyopathy.
Cardiol Res
December 2024
Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
Article Synopsis
- Continuous electrocardiographic (ECG) monitoring during surgery in infants and children is essential to detect potential myocardial pathologies, despite the rarity of these issues in pediatric patients.
- A case is presented involving a 2-year-old child who showed ST segment depression and increased R wave amplitude during surgery, which led to the discovery of undiagnosed hypertrophic cardiomyopathy postoperatively.
- The findings emphasize the importance of recognizing ECG changes and the need for thorough evaluation to prevent complications during and after surgery, even when patients appear asymptomatic.
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