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Drug-associated gingival disorders: a retrospective pharmacovigilance assessment using disproportionality analysis.
BDJ Open
March 2025
Bahrain Defence Force Royal Medical Services, Riffa, Kingdom of Bahrain.
Background: Drug-associated gingival disorders can negatively impact on oral health. This study aimed to utilize the United States Food and Drug Administration Adverse Event Reporting System (USFDA AERS) to comprehensively assess the associations between medications and specific gingival disorders.
Methods: Data were extracted from the USFDA AERS from 2004-2024 using Preferred Terms for eight gingival disorders.
Differences in the Size and Morphology of Masseter Muscle and Mandible Assessed Using Three-Dimensional Computed Tomography.
Aesthetic Plast Surg
February 2025
Department of Cosmetic Injection Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 33 Badachu Road, Beijing, 100144, Shijingshan District, China.
Background: Mandibular angular hypertrophy and hemifacial microsomia involve deformities in the mandibular region, resulting in facial asymmetry that severely affects patients' appearance. This study evaluated the masseter muscle-mandibular correlation in patients with hemifacial microsomia and those with mandibular angular hypertrophy using three-dimensional CT and compared them with normal individuals.
Methods: This study included 310 participants.
The Role of Botulinum Toxin for Masseter Muscle Hypertrophy: A Comprehensive Review.
Toxins (Basel)
February 2025
Physical Medicine and Rehabilitation, Department of Medical and Surgical Sciences, University of Catanzaro "Magna Graecia", 88100 Catanzaro, Italy.
Masticatory muscle hypertrophy (MMH) is a rare clinical phenomenon of uncertain etiology, characterized by a soft swelling near the angle of the jaw. This abnormal enlargement of the masseter muscle can alter the facial profile, leading to aesthetic concerns. Moreover, MMH may also have significant functional repercussions, including pain in the masseter region, often associated with temporomandibular disorders, fatigue, and discomfort during mastication.
View Article and Find Full Text PDFA step forward in enhancing the health-promoting properties of whole tomato as a functional food to lower the impact of non-communicable diseases.
Front Nutr
February 2025
Section of Microbiology, University of Brescia, P. le Spedali Civili, Brescia, Italy.
Nutritional interventions facilitating the consumption of natural, affordable, and environment-compatible health-promoting functional foods are a promising strategy for controlling non-communicable diseases. Given that the complex of tomato micronutrients produces healthier outcomes than lycopene, its major antioxidant component, new strategies to improve the health-supporting properties of the berry are ongoing. In this context, a whole tomato food supplement (WTFS), enriched by 2% olive wastewater containing a complex of healthy nutrients with converging biologic activities, has recently been developed, which is superior to those present in tomato commodities or obtained with whole tomato conventional processing methods.
View Article and Find Full Text PDFPlant Polyphenols as Heart's Best Friends: From Health Properties, to Cellular Effects, to Molecular Mechanisms of Action.
Int J Mol Sci
January 2025
Department of Food, Bioprocessing and Nutrition Sciences, Plants for Human Health Institute, North Carolina State University, Kannapolis, NC 28081, USA.
Polyphenols are micronutrients found in fruits, vegetables, tea, coffee, cocoa, medicinal herbs, fish, crustaceans, and algae. They can also be synthesized using recombinant microorganisms. Interest in plant-derived natural compounds has grown due to their potential therapeutic effects with minimal side effects.
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