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http://dx.doi.org/10.1093/oxfordjournals.jhered.a107554 | DOI Listing |
Cancer Imaging
January 2025
Department of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Background: Previous studies utilizing dual-energy CT (DECT) for evaluating treatment efficacy in nasopharyngeal cancinoma (NPC) are limited. This study aimed to investigate whether the parameters from DECT can predict the response to induction chemotherapy in NPC patients in two centers.
Methods: This two-center retrospective study included patients diagnosed with NPC who underwent contrast-enhanced DECT between March 2019 and November 2023.
Int J Cardiovasc Imaging
January 2025
Department of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Solid-state detector single photon emission computed tomography (SPECT) enables the acquisition of dynamic data for calculation of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Here, we report about our experiences on routine clinical use and robustness using Tc-99 m-sestamibi and Tc-99 m-tetrofosmin. 307 patients underwent dynamic list-mode myocardial perfusion imaging (MPI) and standard static MPI for clinical workup of coronary artery disease on a dedicated cardiac SPECT camera.
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Department of Chemistry, University of Tromsø - The Arctic University of Norway, N9037 Tromsø, Norway.
In this review we discuss the development of methodology for calculating the temperature dependence and thermodynamic activation parameters for chemical reactions in solution and in enzymes, from computer simulations. We outline how this is done by combining the empirical valence bond method with molecular dynamics free energy simulations. In favorable cases it turns out that such simulations can even capture temperature optima for the catalytic rate.
View Article and Find Full Text PDFJ Cardiovasc Comput Tomogr
January 2025
Division of Pediatric Cardiology, Department of Pediatrics, University of Utah, United States; Intermountain Healthcare - Primary Children's Hospital, United States.
Background: Cardiac Computed Tomography (CCT) is increasingly used to provide 2D, 3D and 4D information in patients with congenital heart disease of all ages. Historically, negotiated rates for professional and technical fees associated with cardiac imaging were confidential, with variability in professional, technical and global charges, reimbursement and cost to patients for the same current procedural terminology (CPT) code at different institutions. Billing transparency is a key component of both the CARE act passed in 2020 and the Health Care PRICE Transparency Act 2.
View Article and Find Full Text PDFEur Respir J
January 2025
Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Background: The role of epigenetic aging in the environmental pathogenesis and prognosis of fibrotic interstitial lung disease (fILD) is unclear. We evaluated whether ambient particulate matter ≤2.5 μm (PM) and neighbourhood disadvantage exposures are associated with accelerated epigenetic aging, and whether epigenetic age is associated with adverse clinical outcomes in patients with fILD.
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