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Explainable machine learning for early predicting treatment failure risk among patients with TB-diabetes comorbidity.
Sci Rep
March 2024
Department of Endocrinology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui, People's Republic of China.
Article Synopsis
- The study evaluates treatment outcomes for diabetic patients with tuberculosis (TB-DM) using machine learning algorithms on electronic medical records from 429 patients at Chongqing Public Health Medical Center.
- Researchers utilized the Boruta algorithm to identify key factors predicting treatment success, selecting 9 important features from an initial 69, with resistance type being the most significant.
- The best performing model, XGBoost, achieved an impressive AUC of 0.9281, indicating strong predictive ability for treatment failure, and highlights the potential of machine learning to enhance TB-DM treatment strategies, especially in low and middle-income countries.
Objective: The aim: To investigate the features of coagulation homeostasis in patients with liver cirrhosis (LC) in COVID-19 infection.
Patients And Methods: Materials and methods: At the clinical base of the Department of Propaedeutics of Internal Medicine, 32 patients with LC infected with COVID-19 were examined - 1 Group of patients. The study also included 30 patients with LC who were not infected with COVID-19 (2 Group of patients).
Evolution of Hemostasis Testing: A Personal Reflection Covering over 40 Years of History.
Semin Thromb Hemost
February 2024
Department of Haematology, Institute of Clinical Pathology and Medical Research (ICPMR), Sydney Centres for Thrombosis and Haemostasis, NSW Health Pathology, Westmead Hospital, Westmead, NSW Australia.
There is no certainty in change, other than change is certain. As celebrates 50 years of publication, I felt it appropriate to reflect on my own 40-year plus scientific career. My career in the thrombosis and hemostasis field did not start until 1987, but the subsequent 35 years reflected a period of significant change in associated disease diagnostics.
View Article and Find Full Text PDFINTRAOPERATIVE LEVELS OF COAGULATION FACTORS IN PATIENTS TREATED WITH OPEN AND ENDOVASCULAR REVASCULARIZATION OF OCCLUDED TIBIAL ARTERIES.
Georgian Med News
February 2022
1I. Horbachevsky Ternopil National Medical University, Department of Surgery №2; Ukraine.
Aims - to determine levels of specific coagulation factors pre-operatively and intraoperatively in patients treated with either open or endovascular surgery for occlusion of infrainguinal arteries. Study design: Randomized controlled trial. Methodology: The study included 96 patients with atherosclerotic stenotic-occlusion lesions of the infrainguinal arteries.
View Article and Find Full Text PDF[The diagnosis and management of von Willebrand disease].
Rinsho Ketsueki
September 2021
Department of Transfusion Medicine, Nagoya University Hospital.
Von Willebrand disease (VWD) is a congenital bleeding disorder caused by quantitative and qualitative abnormalities in von Willebrand factor (VWF). VWD was first reported in 1926 by Dr. Erik von Willebrand, a Swedish physician, who reported a bleeding disorder in a family.
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